Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free

Novus Biologicals | Catalog # NBP3-26035

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Vertebrate

Applications

Multiplex Immunofluorescence, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM456 expressed in HEK293

Format

Azide and BSA Free
View all Histone H2B Primary Antibodies »

Product Specifications

Immunogen

An acetyl-peptide corresponding to Histone H2B [Lys11] (Uniprot # P62807)

Specificity

This antibody reacts to Histone H2B acetylated at Lysine 11. No cross reactivity with other acetylated Lysines in histones.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free

Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free

Multiplex Immunoassay: Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free [NBP3-26035] -

Multiplex Immunoassay: Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free [NBP3-26035] - RM456 specifically reacts to Histone H2B acetylated at Lysine 11 (K11ac). No cross reactivity with non-modified Lysine 11, or other acethylations in histone H2B.
Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free

Western Blot: Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free [NBP3-26035] -

Western Blot: Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free [NBP3-26035] - Western Blot of acid extracts of HeLa cells treated (+) or untreated (-) with sodium butyrate, using Clone RM456 at 0.002 ug/mL.

Applications for Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free

Application
Recommended Usage

ELISA

0.2 ug/mL - 1 ug/mL

Western Blot

0.001 ug/mL - 0.01 ug/mL

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Histone H2B

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility tothe cellular machineries which require DNA as a template. Histones thereby play a central role in transcriptionregulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set ofpost-translational modifications of histones, also called histone code, and nucleosome remodeling

Long Name

H2B Histone Family

Alternate Names

HIST1H2BK

Gene Symbol

H2BC18

Additional Histone H2B Products

Product Documents for Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Histone H2B [ac Lys11] Antibody (RM456) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Epigenetics

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