HSP90 alpha Antibody [FITC]

Novus Biologicals | Catalog # NBP1-77682F

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Polyclonal Rabbit IgG
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Product Specifications

Immunogen

A synthetic peptide made to an N-terminal portion of the human Hsp90A protein (between residues 1-70) [UniProt P07900]

Localization

Cytoplasm. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for HSP90 alpha Antibody [FITC]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

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Advanced Features

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  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: HSP90 alpha

Heat shock protein 90-1a (HSP90-1a) is a myosin chaperone involved in heat shock responses, as well as in myofibrillogenesis. It is known to interact with histone methyltransferases, influencing epigenetic changes in certain pathways. It interacts with TERT to assemble the telomerase holoenzyme complex, which is critical for addition of DNA to telomeric ends. It also is important in thick and thin filament organization, influencing the formation and maintenance of sarcomere characteristics. It is highly expressed in skeletal and cardiac muscles.

Long Name

Heat Shock Protein 90 alpha

Alternate Names

HSP86, HSP89A, HSP90A, HSP90AA1, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, LAP2

Gene Symbol

HSP90AA1

Additional HSP90 alpha Products

Product Documents for HSP90 alpha Antibody [FITC]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for HSP90 alpha Antibody [FITC]

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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Associated Pathways

Apoptosis Signaling Pathway Apoptosis Signaling Pathway Thumbnail