Human 5-HT2B Alexa Fluor® 594-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: 5-HT2B

HTR2B is a G-protein coupled receptor for serotonin. The 5HT2 receptors mediate many of the central and peripheral physiologic functions of serotonin. 5HT2B plays a role in the regulation of dopamine and serotonin release, serotonin uptake and in the regulation of extracellular dopamine and serotonin levels. It also plays a role in pulmonary vasoconstriction and regulating cardiac structure and functions. 5HT2B receptors were shown to be expressed in human failing heart and have been strongly implicated in drug induced valvular heart disease.

Product Datasheets

Related Research Areas

• G Protein-Coupled Receptors in Immune Responses
• Neurotransmitter G Protein-Coupled Receptors
• Neurotransmitter Receptors in Blood Pressure Regulation
• Neurotransmitter Receptors on Endothelial Cells
• Neurotransmitter Receptors on VSMC