Human ABI1 Alexa Fluor™ Plus 594‑conjugated Antibody

R&D Systems | Catalog # FAB10249AFP594

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunocytochemistry

Label

Alexa Fluor Plus 594 (Excitation = 590 nm, Emission = 618 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 1013203
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Product Specifications

Specificity

Detects human ABI1 in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human ABI1 Alexa Fluor™ Plus 594‑conjugated Antibody

Application
Recommended Usage

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ABI1

Abelson Interactor 1 (ABI1) is an adaptor protein involved in cytoskeletal reorganization and EGFR signaling. Overexpression of ABI1 inhibits EGF-induced activation of Erks which negatively regulate cell growth and transformation. In the brain, ABI1 seems to regulate dendritic outgrowth and determines the shape and number of synaptic contacts of developing neurons.

References

  1. UniProt: The Universal Protein Knowledgebase. (2017)  Nucleic Acids Res. 45: D158-D169.
  2. Fan. P.-D. and S.P. Goff (2000) Mol. Cell. Biol. 20:7591.
  3. Xiong X. et al. (2008) Biochim Biophy. Acta 1783:737.

Long Name

Abl Interactor 1

Alternate Names

ABI-1, ABLBP4, E3B1, NAP1BP, SSH3BP, SSH3BP1

Entrez Gene IDs

10006 (Human)

Gene Symbol

ABI1

UniProt

Additional ABI1 Products

Product Documents for Human ABI1 Alexa Fluor™ Plus 594‑conjugated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human ABI1 Alexa Fluor™ Plus 594‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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Protocols

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