Human BRIX Alexa Fluor® 405-conjugated Antibody

Catalog # Availability Size / Price Qty
AF4024V-100UG

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Human BRIX Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human BRIX in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human BRIX
Ser131-Lys353
Accession # Q8TDN6
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: BRIX

BRIX (Biogenesis of ribosomes in Xenopus; also BRIX domain-containing protein 2) is a 41 kDa (predicted) member of the BXDC2 family of proteins. It is found in nucleoli, and appears to participate in the formation of a complex associated with pre-rRNA and enzymes that generate 60S ribosomal subunits. Human BRIX is 353 amino acids (aa) in length. It is characterized by the presence of a BRIX domain that lies between aa 60‑249. There is one splice variant that shows a 17 aa substitution for aa 11‑27. Over aa 131‑353, human BRIX shares 93% aa identity with mouse BRIX.

Long Name
Brix Domain Containing 2
Entrez Gene IDs
55299 (Human); 67832 (Mouse); 294799 (Rat)
Alternate Names
brix domain containing 2; Brix domain-containing protein 2; BRIX; BRIX1; BRIXBXDC2; BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); BXDC2; FLJ11100; ribosome biogenesis protein BRX1 homolog

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