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Human BRIX Alexa Fluor® 594-conjugated Antibody

Catalog #: AF4024T Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF4024T-100UG

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human BRIX Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human BRIX in direct ELISAs and Western blots.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human BRIX
Ser131-Lys353
Accession # Q8TDN6
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: BRIX

BRIX (Biogenesis of ribosomes in Xenopus; also BRIX domain-containing protein 2) is a 41 kDa (predicted) member of the BXDC2 family of proteins. It is found in nucleoli, and appears to participate in the formation of a complex associated with pre-rRNA and enzymes that generate 60S ribosomal subunits. Human BRIX is 353 amino acids (aa) in length. It is characterized by the presence of a BRIX domain that lies between aa 60‑249. There is one splice variant that shows a 17 aa substitution for aa 11‑27. Over aa 131‑353, human BRIX shares 93% aa identity with mouse BRIX.

Long Name
Brix Domain Containing 2
Entrez Gene IDs
55299 (Human); 67832 (Mouse); 294799 (Rat)
Alternate Names
brix domain containing 2; Brix domain-containing protein 2; BRIX; BRIX1; BRIXBXDC2; BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); BXDC2; FLJ11100; ribosome biogenesis protein BRX1 homolog

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