BTLA (B- and T-lymphocyte attenuator; CD272) is a transmembrane immunoregulatory glycoprotein that is expressed on T cells, B cells, macrophages, dendritic cells, and NK cells. Its expression is low in naïve T cells and increases during antigen-specific induction of anergy. In B cells, BTLA expression is highest in mature naïve cells. BTLA binds to HVEM and negatively regulates homeostasis and inflammatory activation of CD8+ memory T cells and gamma/delta T cells.
Human BTLA (NP_001078826) VersaClone cDNA
R&D Systems | Catalog # RDC1414
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: BTLA
Long Name
B- And T-Lymphocyte Attenuator
Alternate Names
CD272
Gene Symbol
BTLA
UniProt
Additional BTLA Products
Product Documents for Human BTLA (NP_001078826) VersaClone cDNA
Product Specific Notices for Human BTLA (NP_001078826) VersaClone cDNA
For research use only
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