Human BTN1A1 (NP_001723) VersaClone cDNA

R&D Systems | Catalog # RDC0819

R&D Systems
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Key Product Details

Species

Human

Accession Number

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Background: BTN1A1/Butyrophilin

Butyrophilin 1A1 (BTN1A1) is a B7-related protein in a family that may show co-stimulatory/inhibitory function. BTN1A1 binds to xanthine oxidoreductase (XOR) and is essential in the control of milk fat globule secretion. The B30.2 domain of butyrophilins can sense changes in intracellular phopho-antigen (pAg) concentrations. Its binding to pAg leads to gamma-delta T cell activation. BTN1A1 inhibits CD4+ T cell proliferation and reduces IL-2 and IFN-gamma expression. BTN1A1 has a protective effect against the development of experimental autoimmune encephalomyelitis (EAE).

Alternate Names

BTN, BTN1A1

Entrez Gene IDs

696 (Human); 12231 (Mouse); 306956 (Rat)

Gene Symbol

BTN1A1

UniProt

Additional BTN1A1/Butyrophilin Products

Product Documents for Human BTN1A1 (NP_001723) VersaClone cDNA

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Product Specific Notices for Human BTN1A1 (NP_001723) VersaClone cDNA

For research use only

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