Human Caveolin-3 Alexa Fluor® 750-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: Caveolin-3

Caveolin-3 is an 18 kDa member of the Caveolin family of proteins which are major protein components of plasma membrane caveolae. It is preferentially expressed in muscle cells where it regulates the localization and activity of potassium channels and the nicotinic acetylcholine receptor. Caveolin-3 mutations are associated with several skeletal muscle defects. It contains a central membrane-embedded sequence (aa 84-104) flanked by two cytoplasmic domains (aa 1-83 and 105-151). Over aa 1-83, human Caveolin-3 shares 94% aa identity with mouse and rat Caveolin-3.

Product Datasheets

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