Human CCL2/MCP-1 Quantikine ELISA Kit

  (149 citations)
(5 Reviews)
    
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Product Details
Assay Procedure
Citations (149)
FAQs
Supplemental Products
Reviews
  • Assay Type
    Solid Phase Sandwich ELISA
  • Format
    96-well strip plate
  • Assay Length
    3.5 hours or 4.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (200 uL), Serum (100 uL), EDTA Plasma (100 uL), Heparin Plasma (100 uL), Citrate Plasma (100 uL), Urine (100 uL)
  • Sensitivity
    10 pg/mL
  • Assay Range
    31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine)
  • Specificity
    Natural and recombinant human MCP-1
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    No significant interference observed with available related molecules.
Control Available
QC01-1 , Quantikine Immunoassay Control Group 1 - Please Inquire
Product Summary
The Quantikine Human MCP-1 Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure MCP-1 in cell culture supernates, serum, plasma, and urine. It contains E. coli-expressed recombinant human MCP-1 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate recombinant human MCP-1. Results obtained using natural human MCP-1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human MCP-1.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision
Cell Culture Supernates, Urine
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 78.2 360 1079 76 360 1086
Standard Deviation 3.3 17.7 63.5 4.5 17.2 48.5
CV% 4.2 4.9 5.9 5.9 4.8 4.5

Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 76.7 364 1121 74.2 352 1076
Standard Deviation 6 17.1 54.4 5 20.5 49.4
CV% 7.8 4.7 4.9 6.7 5.8 4.6

Recovery

The recovery of MCP-1 spiked to three levels throughout the range of the assay was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=5) 96 88-107
Citrate Plasma (n=5) 100 94-107
EDTA Plasma (n=5) 96 92-102
Heparin Plasma (n=5) 102 94-114
Serum (n=5) 103 92-113
Urine (n=5) 92 85-100
Linearity
To assess the linearity of the assay, samples were spiked with high concentrations of MCP-1 and diluted with the appropriate Calibrator Diluent to produce samples with values within the dynamic range of the assay.
 CCL2/JE/MCP-1 [HRP]
Product Datasheets

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Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: CCL2/JE/MCP-1
CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.
  • Entrez Gene IDs:
    6347 (Human); 20296 (Mouse); 24770 (Rat); 403981 (Canine)
  • Alternate Names:
    C-C motif chemokine ligand 2; CCL2; GDCF-2; HC11; HSMCR30; MCAF; Mcp1; MCP-1; SCYA2; SMC-CF
Related Research Areas
Assay Procedure
Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 50 µL Assay Diluent for Serum & Plasma Samples Only
  4.   For Serum & Plasma Samples Only: Add 50 µL of Assay Diluent to each well.

  5. 200 µL Standard, Control, or Sample
  6.   Add 200 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate each well and wash, repeating the process twice for a total of 3 washes.

  8. 200 µL Conjugate
  9.   Add 200 µL of Conjugate to each well.
  10.   For Serum & Plasma Samples: Cover with a new plate sealer, and incubate at room temperature for 2 hours.
    For Cell Culture Supernate & Urine Samples: Cover with a new plate sealer, and incubate at room temperature for 1 hour.
  11.   Aspirate and wash 3 times.

  12. 200 µL Substrate Solution
  13.   Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.

  14. 50 µL Stop Solution
  15. Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

149 Citations: Showing 1 - 10
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Species
Sample Type
  1. Weight loss has an additive effect on the proteinuria reduction of angiotensin II receptor blockers in hypertensive patients with chronic kidney disease
    Authors: SY Ahn, DK Kim, SS Han, JH Park, SJ Shin, SH Lee, BS Choi, CS Lim, S Kim, HJ Chin
    Kidney Res Clin Pract, 2018;37(1):49-58.
    Species: Human
    Sample Type: Urine
  2. Canagliflozin inhibits interleukin-1?-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms
    Authors: SJ Mancini, D Boyd, OJ Katwan, A Strembitsk, TA Almabrouk, S Kennedy, TM Palmer, IP Salt
    Sci Rep, 2018;8(1):5276.
    Species: Human
    Sample Type: Cell Culture Supernates
  3. mTOR pathway activation drives lung cell senescence and emphysema
    Authors: A Houssaini, M Breau, K Kebe, S Abid, E Marcos, L Lipskaia, D Rideau, A Parpaleix, J Huang, V Amsellem, N Vienney, P Validire, B Maitre, A Attwe, C Lukas, D Vindrieux, J Boczkowski, G Derumeaux, M Pende, D Bernard, S Meiners, S Adnot
    JCI Insight, 2018;3(3):.
    Species: Human
    Sample Type: Cell Culture Supernates
  4. Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients
    Authors: G Annibalini, F Lucertini, D Agostini, L Vallorani, A Gioacchini, E Barbieri, M Guescini, L Casadei, A Passalia, M Del Sal, G Piccoli, M Andreani, A Federici, V Stocchi
    Oxid Med Cell Longev, 2017;2017(0):3937842.
    Species: Human
    Sample Type: Plasma
  5. Visceral fat area is a strong predictor of leukocyte cell-derived chemotaxin 2, a potential biomarker of dyslipidemia
    Authors: K Tanisawa, H Taniguchi, X Sun, T Ito, R Kawakami, S Sakamoto, M Higuchi
    PLoS ONE, 2017;12(3):e0173310.
    Species: Human
    Sample Type: Serum
  6. New Markers of Inflammation and Tubular Damage in Children with Chronic Kidney Disease
    Authors: K Musia?, A Bargenda, D Dro?d?, D Zwoli?ska
    Dis. Markers, 2017;2017(0):9389432.
    Species: Human
    Sample Type: Urine
  7. Prostate cancer downregulated SIRP-? modulates apoptosis and proliferation through p38-MAPK/NF-?B/COX-2 signaling
    Authors: C Yao, G Li, M Cai, Y Qian, L Wang, L Xiao, F Thaiss, B Shi
    Oncol Lett, 2017;13(6):4995-5001.
    Species: Human
    Sample Type: Cell Culture Supernates
  8. C1q/TNF-related protein 9 inhibits the cholesterol-induced Vascular smooth muscle cell phenotype switch and cell dysfunction by activating AMP-dependent kinase
    Authors: Q Liu, H Zhang, J Lin, R Zhang, S Chen, W Liu, M Sun, W Du, J Hou, B Yu
    J. Cell. Mol. Med., 2017;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  9. Osteoprotegerin Is a New Regulator of Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy
    Authors: AM Abu El-Asr, S Struyf, G Mohammad, M Gouwy, P Rytinx, MM Siddiquei, C Hernández, K Alam, A Mousa, G De Hertogh, G Opdenakker, R Simó
    Invest. Ophthalmol. Vis. Sci., 2017;58(7):3189-3201.
    Species: Human
    Sample Type: Vitreous Fluid
  10. N-Caffeoyltryptamine, a Potent Anti-Inflammatory Phenolic Amide, Suppressed MCP-1 Expression in LPS-stimulated THP-1 Cells and Rats Fed a High-Fat Diet
    Authors: JB Park
    Int J Mol Sci, 2017;18(6):.
    Species: Rat
    Sample Type: Plasma
  11. Cerebrospinal fluid and serum IL-8, CCL2, and ICAM-1 concentrations in astrocytic brain tumor patients.
    Authors: Koper O, Kaminska J, Sawicki K, Reszec J, Rutkowski R, Jadeszko M, Mariak Z, Dymicka-Piekarska V, Kemona H
    Ir J Med Sci, 2017;0(0):.
    Species: Human
    Sample Type: Serum
  12. Epigallocatechin Gallate-Loaded Gelatin-g-Poly(N-Isopropylacrylamide) as a New Ophthalmic Pharmaceutical Formulation for Topical Use in the Treatment of Dry Eye Syndrome
    Authors: LJ Luo, JY Lai
    Sci Rep, 2017;7(1):9380.
    Species: Human
    Sample Type: Cell Culture Supernates
  13. Monocyte chemoattractant protein-1 polymorphism interaction with spirulina immunomodulatory effects in healthy Korean elderly: A 16 week, double-blind randomized clinical trial
    Authors: HJ Park, HS Lee
    Nutr Res Pract, 2017;11(4):290-299.
    Species: Human
    Sample Type: Plasma
  14. Serum levels of leptin and adiponectin and clinical parameters in women with fibromyalgia and overweight/obesity
    Authors: ES Paiva, A Andretta, ED Batista, MM Lobo, RC Miranda, R Nisihara, ME Schieferde, CL Boguszewsk
    Arch Endocrinol Metab, 2017;0(0):0.
    Species: Human
    Sample Type: Serum
  15. Short-chain fatty acids, GPR41 and GPR43 ligands, inhibit TNF-?-induced MCP-1 expression by modulating p38 and JNK signaling pathways in human renal cortical epithelial cells
    Authors: M Kobayashi, D Mikami, H Kimura, K Kamiyama, Y Morikawa, S Yokoi, K Kasuno, N Takahashi, T Taniguchi, M Iwano
    Biochem. Biophys. Res. Commun, 2017;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  16. TWEAK/Fn14 promotes pro-inflammatory cytokine secretion in hepatic stellate cells via NF-?B/STAT3 pathways
    Authors: A Wang, F Zhang, H Xu, M Xu, Y Cao, C Wang, Y Xu, M Su, M Zhang, Y Zhuge
    Mol. Immunol., 2017;87(0):67-75.
    Species: Human
    Sample Type: Cell Culture Supernates
  17. Urine Epidermal Growth Factor, Monocyte Chemoattractant Protein-1 or Their Ratio as Biomarkers for Interstitial Fibrosis and Tubular Atrophy in Primary Glomerulonephritis
    Authors: Supanat Worawichaw
    Kidney Blood Press. Res, 2016;41(6):997-1007.
    Species: Human
    Sample Type: Urine
  18. Activation of the vitamin D receptor selectively interferes with calcineurin-mediated inflammation: a clinical evaluation in the abdominal aortic aneurysm
    Authors: Arend Jan Nieuwland
    Lab Invest, 2016;0(0):.
    Species: Human
    Sample Type: Tissue Homogenates
  19. Plasma Levels of Monocyte Chemoattractant Protein-1, n-Terminal Fragment of Brain Natriuretic Peptide and Calcidiol Are Independently Associated with the Complexity of Coronary Artery Disease
    PLoS ONE, 2016;11(5):e0152816.
    Species: Human
    Sample Type: Plasma
  20. Sterile inflammation as a factor in human male infertility: Involvement of Toll like receptor 2, biglycan and peritubular cells
    Sci Rep, 2016;6(0):37128.
    Species: Human
    Sample Type: Whole Cells
  21. Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication
    PLoS Pathog, 2016;12(12):e1006048.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Type: Plasma
  22. Secreted ectodomain of sialic acid-binding Ig-like lectin-9 and monocyte chemoattractant protein-1 promote recovery after rat spinal cord injury by altering macrophage polarity.
    Authors: Matsubara K, Matsushita Y, Sakai K, Kano F, Kondo M, Noda M, Hashimoto N, Imagama S, Ishiguro N, Suzumura A, Ueda M, Furukawa K, Yamamoto A
    J Neurosci, 2015;35(6):2452-64.
    Species: Rat
    Sample Type: Cell Culture Supernates
  23. The impact of concomitant pulmonary infection on immune dysregulation in Pneumocystis jirovecii pneumonia.
    Authors: Chou C, Lin F, Tsai H, Chang S
    BMC Pulm Med, 2014;14(0):182.
    Species: Human
    Sample Type: BALF
  24. PPM1A is a RelA phosphatase with tumor suppressor-like activity.
    Authors: Lu X, An H, Jin R, Zou M, Guo Y, Su P, Liu D, Shyr Y, Yarbrough W
    Oncogene, 2014;33(22):2918-27.
    Species: Human
    Sample Type: Cell Culture Supernates
  25. ACE inhibitors potently reduce vascular inflammation, results of an open proof-of-concept study in the abdominal aortic aneurysm.
    Authors: Kortekaas K, Meijer C, Hinnen J, Dalman R, Xu B, Hamming J, Lindeman J
    PLoS ONE, 2014;9(12):e111952.
    Species: Human
    Sample Type: Tissue Homogenates
  26. Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination.
    Authors: Zhan Z, Xie X, Cao H, Zhou X, Zhang X, Fan H, Liu Z
    Autophagy, 2014;10(2):257-68.
    Species: Human
    Sample Type: Cell Culture Supernates
  27. Nuclear NF-kappaB p65 in peripheral blood mononuclear cells correlates with urinary MCP-1, RANTES and the severity of type 2 diabetic nephropathy.
    Authors: Yi B, Hu X, Zhang H, Huang J, Liu J, Hu J, Li W, Huang L
    PLoS ONE, 2014;9(6):e99633.
    Species: Human
    Sample Type: Urine
  28. Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction.
    Authors: Wang T, Green L, Gupta S, Kim C, Wang L, Almodovar S, Flores S, Prudovsky I, Jolicoeur P, Liu Z, Clauss M
    PLoS ONE, 2014;9(3):e91063.
    Species: Human
    Sample Type: Cell Culture Supernates
  29. Sulfur compounds block MCP-1 production by Mycoplasma fermentans-infected macrophages through NF-kappaB inhibition.
    Authors: Benedetti F, Davinelli S, Krishnan S, Gallo R, Scapagnini G, Zella D, Curreli S
    J Transl Med, 2014;12(0):145.
    Species: Human
    Sample Type: Cell Culture Supernates
  30. Bisphosphonates inhibit osteosarcoma-mediated osteolysis via attenuation of tumor expression of MCP-1 and RANKL.
    Authors: Ohba T, Cole H, Cates J, Slosky D, Haro H, Ando T, Schwartz H, Schoenecker J
    J Bone Miner Res, 2014;29(6):1431-45.
    Species: Human
    Sample Type: Cell Culture Supernates
  31. Effect of Sfrp5 on cytokine release and insulin action in primary human adipocytes and skeletal muscle cells.
    Authors: Carstensen M, Wiza C, Rohrig K, Fahlbusch P, Roden M, Herder C, Ouwens D
    PLoS ONE, 2014;9(1):e85906.
    Species: Human
    Sample Type: Cell Culture Supernates
  32. Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy.
    Authors: Zhang Y, Chen H, Sun C, Wang H, Liu M, Li Y, Nie X, Du M, Li D, Zhang J
    PLoS ONE, 2014;9(6):e99612.
    Species: Human
    Sample Type: Cell Culture Supernates
  33. The expression of cytokines and chemokines in the blood of patients with severe weight loss from anorexia nervosa: an exploratory study.
    Authors: Pisetsky D, Trace S, Brownley K, Hamer R, Zucker N, Roux-Lombard P, Dayer J, Bulik C
    Cytokine, 2014;69(1):110-5.
    Species: Human
    Sample Type: Cell Culture Supernates
  34. Early B cell factor 1 regulates adipocyte morphology and lipolysis in white adipose tissue.
    Authors: Gao H, Mejhert N, Fretz J, Arner E, Lorente-Cebrian S, Ehrlund A, Dahlman-Wright K, Gong X, Stromblad S, Douagi I, Laurencikiene J, Dahlman I, Daub C, Ryden M, Horowitz M, Arner P
    Cell Metab, 2014;19(6):981-92.
    Species: Human
    Sample Type: Cell Culture Supernates
  35. Astrocyte elevated gene-1 is a novel modulator of HIV-1-associated neuroinflammation via regulation of nuclear factor-kappaB signaling and excitatory amino acid transporter-2 repression.
    Authors: Vartak-Sharma N, Gelman B, Joshi C, Borgamann K, Ghorpade A
    J Biol Chem, 2014;289(28):19599-612.
    Species: Human
    Sample Type: Cell Culture Supernates
  36. Coinfection with human herpesvirus 8 is associated with persistent inflammation and immune activation in virologically suppressed HIV-infected patients.
    Authors: Masia M, Robledano C, Ortiz de la Tabla V, Antequera P, Lumbreras B, Hernandez I, Gutierrez F
    PLoS ONE, 2014;9(8):e105442.
    Species: Human
    Sample Type: Plasma
  37. Effects of high-dose cholecalciferol on serum markers of inflammation and immunity in patients with early chronic kidney disease.
    Authors: Alvarez J, Zughaier S, Law J, Hao L, Wasse H, Ziegler T, Tangpricha V
    Eur J Clin Nutr, 2013;67(3):264-9.
    Species: Human
    Sample Type: Cell Culture Supernates
  38. Leukemia cells induce changes in human bone marrow stromal cells.
    Authors: Civini S, Jin P, Ren J, Sabatino M, Castiello L, Jin J, Wang H, Zhao Y, Marincola F, Stroncek D
    J Transl Med, 2013;11(0):298.
    Species: Human
    Sample Type: Cell Culture Supernates
  39. Increased Eotaxin and MCP-1 Levels in Serum from Individuals with Periodontitis and in Human Gingival Fibroblasts Exposed to Pro-Inflammatory Cytokines.
    Authors: Bostrom E, Kindstedt E, Sulniute R, Palmqvist P, Majster M, Holm C, Zwicker S, Clark R, Onell S, Johansson I, Lerner U, Lundberg P
    PLoS ONE, 2013;10(8):e0134608.
  40. Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells.
    Authors: Smrz D, Bandara G, Beaven M, Metcalfe D, Gilfillan A
    Eur J Immunol, 2013;43(7):1873-82.
    Species: Human
    Sample Type: Cell Culture Supernates
  41. Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension.
    Authors: Sawada H, Saito T, Nickel N, Alastalo T, Glotzbach J, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai Y, Perez V, Kim Y, Wang L, Chen P, Spiekerkoetter E, Mitani Y, Gurtner G, Sarnow P, Rabinovitch M
    J Exp Med, 2013;211(2):263-80.
    Species: Human
    Sample Type: Cell Culture Supernates
  42. Monocyte chemotactic protein-1 (MCP-1) in patients with chronic schistosomiasis mansoni: evidences of subclinical renal inflammation.
    Authors: Hanemann A, Liborio A, Daher E, Martins A, Pinheiro M, Sousa M, Bezerra F
    PLoS ONE, 2013;8(11):e80421.
    Species: Human
    Sample Type: Urine
  43. Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer.
    Authors: Schauer D, Starlinger P, Reiter C, Jahn N, Zajc P, Buchberger E, Bachleitner-Hofmann T, Bergmann M, Stift A, Gruenberger T, Brostjan C
    PLoS ONE, 2012;7(9):e44450.
    Species: Human
    Sample Type: Plasma
  44. Prevalence of Chronic Kidney Disease and Progression of Disease Over Time among Patients Enrolled in the Houston West Nile Virus Cohort.
    Authors: Nolan MS, Podoll AS, Hause AM
    PLoS ONE, 2012;7(7):e40374.
    Species: Human
    Sample Type: Urine
  45. Hypoxia potentiates glioma-mediated immunosuppression.
    Authors: Wei J, Wu A, Kong LY, Wang Y, Fuller G, Fokt I, Melillo G, Priebe W, Heimberger AB
    PLoS ONE, 2012;6(1):e16195.
    Species: Human
    Sample Type: Cell Culture Supernates
  46. Increased levels of inflammatory cytokines and endothelin-1 in alveolar macrophages from patients with chronic heart failure.
    Authors: Sikkeland LI, Dahl CP, Ueland T, Andreassen AK, Gude E, Edvardsen T, Holm T, Yndestad A, Gullestad L, Kongerud J, Aukrust P, ØIe E
    PLoS ONE, 2012;7(5):e36815.
  47. Mycobacterium bovis bacilli Calmette-Guerin regulates leukocyte recruitment by modulating alveolar inflammatory responses.
    Authors: Andersson M, Lutay N, Hallgren O, Westergren-Thorsson G, Svensson M, Godaly G
    Innate Immun, 2012;18(3):531-40.
    Species: Human
    Sample Type: Cell Culture Supernates
  48. Exenatide as a weight-loss therapy in extreme pediatric obesity: a randomized, controlled pilot study.
    Authors: Kelly AS, Metzig AM, Rudser KD, Fitch AK, Fox CK, Nathan BM, Deering MM, Schwartz BL, Abuzzahab MJ, Gandrud LM, Moran A, Billington CJ, Schwarzenberg SJ
    Obesity (Silver Spring), 2012;20(2):364-70.
    Species: Human
    Sample Type: Plasma
  49. Anti-inflammatory effects of methoxyphenolic compounds on human airway cells.
    Authors: Houser KR, Johnson DK, Ishmael FT
    J Inflamm (Lond), 2012;9(0):6.
    Species: Human
    Sample Type: Cell Culture Supernates
  50. Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue Fever.
    Authors: de-Oliveira-Pinto LM, Marinho CF, Povoa TF, de Azeredo EL, de Souza LA, Barbosa LD, Motta-Castro AR, Alves AM, Avila CA, de Souza LJ, da Cunha RV, Damasco PV, Paes MV, Kubelka CF
    PLoS ONE, 2012;7(7):e38527.
    Species: Human
    Sample Type: Plasma
  51. Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury.
    Authors: Quesnel C, Piednoir P, Gelly J, Nardelli L, Garnier M, Lecon V, Lasocki S, Bouadma L, Philip I, Elbim C, Mentre F, Soler P, Crestani B, Dehoux M
    Crit. Care Med., 2012;40(1):21-8.
    Species: Human
    Sample Type: BALF
  52. A composite urine biomarker reflects interstitial inflammation in lupus nephritis kidney biopsies.
    Authors: Zhang X, Nagaraja HN, Nadasdy T
    Kidney Int., 2012;81(4):401-6.
    Species: Human
    Sample Type: Urine
  53. Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.
    Authors: Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK
    J. Immunol., 2012;188(3):1002-10.
    Species: Human
    Sample Type: Cell Culture Supernates
  54. Vascular endothelial growth factor-A (VEGF-A) and chemokine ligand-2 (CCL2) in Amyotrophic Lateral Sclerosis (ALS) patients.
    Authors: Gupta PK, Prabhakar S
    J Neuroinflammation, 2011;8(1):47.
    Species: Human
    Sample Type: Serum
  55. Preclinical Evaluation of Local JAK1 and JAK2 Inhibition in Cutaneous Inflammation.
    Authors: Fridman JS, Scherle PA, Collins R, Burn T, Neilan CL, Hertel D, Contel N, Haley P, Thomas B, Shi J, Collier P, Rodgers JD, Shepard S, Metcalf B, Hollis G, Newton RC, Yeleswaram S, Friedman SM, Vaddi K
    J. Invest. Dermatol., 2011;131(9):1838-44.
    Species: Human
    Sample Type: Cell Culture Supernates
  56. Oral cholecalciferol decreases albuminuria and urinary TGF-beta1 in patients with type 2 diabetic nephropathy on established renin-angiotensin-aldosterone system inhibition.
    Authors: Kim MJ, Frankel AH, Donaldson M, Darch SJ, Pusey CD, Hill PD, Mayr M, Tam FW
    Kidney Int., 2011;80(8):851-60.
    Species: Human
    Sample Type: Urine
  57. Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition.
    Authors: Bunck MC, Diamant M, Eliasson B, Corner A, Shaginian RM, Heine RJ, Taskinen MR, Yki-Jarvinen H, Smith U
    Diabetes Care, 2010;33(8):1734-7.
    Species: Human
    Sample Type: Serum
  58. Distraction osteogenesis induces endothelial progenitor cell mobilization without inflammatory response in man.
    Authors: Lee DY, Cho TJ, Lee HR, Park MS, Yoo WJ, Chung CY, Choi IH
    Bone, 2010;46(3):673-9.
    Species: Human
    Sample Type: Plasma
  59. Cerebrospinal fluid in HIV-1 systemic viral controllers: absence of HIV-1 RNA and intrathecal inflammation.
    Authors: Probasco JC, Deeks SG, Lee E, Hoh R, Hunt PW, Liegler T, Price RW, Spudich SS
    AIDS, 2010;24(7):1001-5.
    Species: Human
    Sample Type: CSF
  60. Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells.
    Authors: Tso GH, Law HK, Tu W
    Stem Cells, 2010;28(5):939-54.
    Species: Human
    Sample Type: Cell Culture Supernates
  61. Rickettsia rickettsii infection of human macrovascular and microvascular endothelial cells reveals activation of both common and cell type-specific host response mechanisms.
    Authors: Rydkina E, Turpin LC, Sahni SK
    Infect. Immun., 2010;78(6):2599-606.
    Species: Human
    Sample Type: Cell Culture Supernates
  62. Monocyte chemoattractant protein-1 (MCP-1)/CCL2 secreted by hepatic myofibroblasts promotes migration and invasion of human hepatoma cells.
    Authors: Dagouassat M, Suffee N, Hlawaty H, Haddad O, Charni F, Laguillier C, Vassy R, Martin L, Schischmanoff PO, Gattegno L, Oudar O, Sutton A, Charnaux N
    Int. J. Cancer, 2010;126(5):1095-108.
    Species: Human
    Sample Type: Cell Culture Supernates
  63. IL-33 mediates inflammatory responses in human lung tissue cells.
    Authors: Yagami A, Orihara K, Morita H
    J. Immunol., 2010;185(10):5743-50.
    Species: Human
    Sample Type: Cell Culture Supernates
  64. HLA-DR+ leukocytes acquire CD1 antigens in embryonic and fetal human skin and contain functional antigen-presenting cells.
    Authors: Schuster C, Vaculik C, Fiala C, Meindl S, Brandt O, Imhof M, Stingl G, Eppel W, Elbe-Burger A
    J. Exp. Med., 2009;206(1):169-81.
    Species: Human
    Sample Type: Cell Culture Supernates
  65. CXCL10 and CCL2 chemokine serum levels in patients with hepatitis C associated with autoimmune thyroiditis.
    Authors: Antonelli A, Ferri C, Fallahi P, Ferrari SM, Frascerra S, Pampana A, Panicucci E, Carpi A, Nicolini A, Ferrannini E
    J. Interferon Cytokine Res., 2009;29(6):345-51.
    Species: Human
    Sample Type: Serum
  66. Smoking, inflammatory patterns and postprandial hypertriglyceridemia.
    Authors: Kabagambe EK, Ordovas JM, Tsai MY, Borecki IB, Hopkins PN, Glasser SP, Arnett DK
    Atherosclerosis, 2009;203(2):633-9.
    Species: Human
    Sample Type: Serum
  67. Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis.
    Authors: Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Froland SS, Olofsson PS, Damas JK, Gullestad L, Hansson GK, Oie E, Aukrust P
    Circ. Res., 2009;104(1):60-8.
    Species: Human
    Sample Type: Cell Culture Supernates
  68. Tumour necrosis factor alpha stimulates the production of monocyte chemoattractants by extravillous trophoblast cells via differential activation of MAPK pathways.
    Authors: Renaud SJ, Sullivan R, Graham CH
    Placenta, 2009;30(4):313-9.
    Species: Human
    Sample Type: Cell Culture Supernates
  69. A plant stanol yogurt drink alone or combined with a low-dose statin lowers serum triacylglycerol and non-HDL cholesterol in metabolic syndrome patients.
    Authors: Plat J, Brufau G, Dallinga-Thie GM, Dasselaar M, Mensink RP
    J. Nutr., 2009;139(6):1143-9.
    Species: Human
    Sample Type: Plasma
  70. HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial.
    Authors: Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, Ubolyam S, Carr A, Ruxungtham K, Hirschel B, Ananworanich J,
    AIDS, 2009;23(8):929-39.
    Species: Human
    Sample Type: Plasma
  71. Cross-sectional relations of multiple inflammatory biomarkers to peripheral arterial disease: The Framingham Offspring Study.
    Authors: Murabito JM, Keyes MJ, Guo CY, Keaney JF, Vasan RS, D'Agostino RB, Benjamin EJ
    Atherosclerosis, 2009;203(2):509-14.
    Species: Human
    Sample Type: Plasma
  72. Serum levels of monocyte chemoattractant protein-1 in periodontal health and disease.
    Authors: Pradeep AR, Daisy H, Hadge P
    Cytokine, 2009;47(2):77-81.
    Species: Human
    Sample Type: Serum
  73. Effect of protein kinase Cbeta inhibition on renal hemodynamic function and urinary biomarkers in humans with type 1 diabetes: a pilot study.
    Authors: Cherney DZ, Konvalinka A, Zinman B, Diamandis EP, Soosaipillai A, Reich H, Lorraine J, Lai V, Scholey JW, Miller JA
    Diabetes Care, 2009;32(1):91-3.
    Species: Human
    Sample Type: Urine
  74. Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia.
    Authors: Troseid M, Seljeflot I, Hjerkinn EM, Arnesen H
    Diabetes Care, 2009;32(3):486-92.
    Species: Human
    Sample Type: Plasma
  75. Intensive insulin therapy decreases urinary MCP-1 and ICAM-1 excretions in incipient diabetic nephropathy.
    Authors: Ye SD, Zheng M, Zhao LL, Qian Y, Yao XM, Ren A, Li SM, Jing CY
    Eur. J. Clin. Invest., 2009;39(11):980-5.
    Species: Human
    Sample Type: Urine
  76. Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts.
    Authors: Mizutani K, Sud S, Pienta KJ
    J. Cell. Biochem., 2009;106(4):563-9.
    Species: Human
    Sample Type: Cell Culture Supernates
  77. Thrombin-induced expression of endothelial CX3CL1 potentiates monocyte CCL2 production and transendothelial migration.
    Authors: Popovic M, Laumonnier Y, Burysek L, Syrovets T, Simmet T
    J. Leukoc. Biol., 2008;84(1):215-23.
    Species: Human
    Sample Type: Cell Culture Supernates
  78. Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
    Authors: Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
    J. Neuroimmunol., 2008;199(1):35-45.
    Species: Human
    Sample Type: Cell Culture Supernates
  79. High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins.
    Authors: Smith C, Halvorsen B, Otterdal K, Waehre T, Yndestad A, Fevang B, Sandberg WJ, Breland UM, Froland SS, Oie E, Gullestad L, Damas JK, Aukrust P
    Cardiovasc. Res., 2008;79(1):195-203.
    Species: Human
    Sample Type: Cell Culture Supernates
  80. The role of capillary density, macrophage infiltration and interstitial scarring in the pathogenesis of human chronic kidney disease.
    Authors: Eardley KS, Kubal C, Zehnder D, Quinkler M, Lepenies J, Savage CO, Howie AJ, Kaur K, Cooper MS, Adu D, Cockwell P
    Kidney Int., 2008;74(4):495-504.
    Species: Human
    Sample Type: Urine
  81. A polymorphism in the CCL2 chemokine gene is associated with asthma risk: a case-control and a family study in Tunisia.
    Authors: Chelbi H, Ghadiri A, Lacheb J, Ghandil P, Hamzaoui K, Hamzaoui A, Combadiere C
    Genes Immun., 2008;9(7):575-81.
    Species: Human
    Sample Type: Plasma
  82. Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation.
    Authors: Zehnder D, Quinkler M, Eardley KS, Bland R, Lepenies J, Hughes SV, Raymond NT, Howie AJ, Cockwell P, Stewart PM, Hewison M
    Kidney Int., 2008;74(10):1343-53.
    Species: Human
    Sample Type: Urine
  83. MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells.
    Authors: Le Quement C, Guenon I, Gillon JY, Lagente V, Boichot E
    Am. J. Physiol. Lung Cell Mol. Physiol., 2008;294(6):L1076-84.
    Species: Human
    Sample Type: Cell Culture Supernates
  84. Exploring human testicular peritubular cells: identification of secretory products and regulation by tumor necrosis factor-alpha.
    Authors: Schell C, Albrecht M, Mayer C, Schwarzer JU, Frungieri MB, Mayerhofer A
    Endocrinology, 2008;149(4):1678-86.
    Species: Human
    Sample Type: Cell Culture Supernates
  85. In vitro induction of a dendritic cell phenotype in primary human acute myelogenous leukemia (AML) blasts alters the chemokine release profile and increases the levels of T cell chemotactic CCL17 and CCL22.
    Authors: Olsnes AM, Ryningen A, Ersvaer E, Bruserud Ø
    J. Interferon Cytokine Res., 2008;28(5):297-310.
    Species: Human
    Sample Type: Cell Culture Supernates
  86. Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases.
    Authors: Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D
    J. Immunol., 2008;181(11):8053-67.
    Species: Human
    Sample Type: BALF
  87. An oil mixture with trans-10, cis-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in postmenopausal women.
    Authors: Tholstrup T, Raff M, Straarup EM, Lund P, Basu S, Bruun JM
    J. Nutr., 2008;138(8):1445-51.
    Species: Human
    Sample Type: Serum
  88. Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6.
    Authors: Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A
    Proc. Natl. Acad. Sci. U.S.A., 2007;104(7):2319-24.
    Species: Human
    Sample Type: Cell Culture Supernates
  89. Panel of markers can accurately predict endometriosis in a subset of patients.
    Authors: Seeber B, Sammel MD, Fan X, Gerton GL, Shaunik A, Chittams J, Barnhart KT
    Fertil. Steril., 2007;89(5):1073-81.
    Species: Human
    Sample Type: Serum
  90. Pleiotrophic and anti-inflammatory effects of pioglitazone precede the metabolic activity in type 2 diabetic patients with coronary artery disease.
    Authors: Forst T, Karagiannis E, Lubben G, Hohberg C, Schondorf T, Dikta G, Drexler M, Morcos M, Danschel W, Borchert M, Pfutzner A
    Atherosclerosis, 2007;197(1):311-7.
    Species: Human
    Sample Type: Plasma
  91. Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease.
    Authors: Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, Gerlitz B, Repici A, Arena V, Malesci A, Panes J, Grinnell BW, Danese S
    J. Clin. Invest., 2007;117(7):1951-60.
    Species: Human
    Sample Type: Whole Cells
  92. Proliferation, differentiation, and cytokine secretion of human umbilical cord blood-derived mononuclear cells in vitro.
    Authors: Neuhoff S, Moers J, Rieks M, Grunwald T, Jensen A, Dermietzel R, Meier C
    Exp. Hematol., 2007;35(7):1119-31.
    Species: Human
    Sample Type: Cell Culture Supernates
  93. Borrelia burgdorferi-induced monocyte chemoattractant protein-1 production in vivo and in vitro.
    Authors: Zhao Z, McCloud B, Fleming R, Klempner MS
    Biochem. Biophys. Res. Commun., 2007;358(2):528-33.
    Species: Human
    Sample Type: Tissue Homogenates
  94. Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose.
    Authors: Harrison ML, Obermueller E, Maisey NR, Hoare S, Edmonds K, Li NF, Chao D, Hall K, Lee C, Timotheadou E, Charles K, Ahern R, King DM, Eisen T, Corringham R, DeWitte M, Balkwill F, Gore M
    J. Clin. Oncol., 2007;25(29):4542-9.
    Species: Human
    Sample Type: Plasma
  95. Newly recruited human monocytes have a preserved responsiveness towards bacterial peptides in terms of CD11b up-regulation and intracellular hydrogen peroxide production.
    Authors: Dadfar E, Jacobson SH, Lundahl J
    Clin. Exp. Immunol., 2007;148(3):573-82.
    Species: Human
    Sample Type: Serum
  96. Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis.
    Authors: Bae E, Kim WJ, Kang YM, Suk K, Koh EM, Cha HS, Ahn KS, Huh TL, Lee WH
    Clin. Exp. Immunol., 2007;148(3):410-8.
    Species: Human
    Sample Type: Cell Culture Supernates
  97. The monocyte chemoattractant protein-1/cognate CC chemokine receptor 2 system affects cell motility in cultured human podocytes.
    Authors: Burt D, Salvidio G, Tarabra E, Barutta F, Pinach S, Dentelli P, Camussi G, Perin PC, Gruden G
    Am. J. Pathol., 2007;171(6):1789-99.
    Species: Human
    Sample Type: Cell Culture Supernates
  98. IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation.
    Authors: Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, Rochester C, Cain H, Chupp G, Yoon HJ, Elias JA
    J. Immunol., 2007;178(3):1948-59.
    Species: Human
    Sample Type: BALF
  99. Neuroinvasion of fluorescein-positive monocytes in acute simian immunodeficiency virus infection.
    Authors: Clay CC, Rodrigues DS, Ho YS, Fallert BA, Janatpour K, Reinhart TA, Esser U
    J. Virol., 2007;81(21):12040-8.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Plasma
  100. L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion.
    Authors: Abe Y, Fornage M, Yang CY, Bui-Thanh NA, Wise V, Chen HH, Rangaraj G, Ballantyne CM
    Atherosclerosis, 2007;192(1):56-66.
    Species: Human
    Sample Type: Cell Culture Supernates
  101. Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1.
    Authors: Canault M, Leroyer AS, Peiretti F, Leseche G, Tedgui A, Bonardo B, Alessi MC, Boulanger CM, Nalbone G
    Am. J. Pathol., 2007;171(5):1713-23.
    Species: Human
    Sample Type: Cell Culture Supernates
  102. Specificity of immunomodulator secretion in urinary samples in response to infection by alpha-hemolysin and CNF1 bearing uropathogenic Escherichia coli.
    Authors: Real JM, Munro P, Buisson-Touati C, Lemichez E, Boquet P, Landraud L
    Cytokine, 2007;37(1):22-5.
    Species: Human
    Sample Type: Urine
  103. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
    Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
    J. Exp. Med., 2006;203(12):2763-77.
    Species: Human
    Sample Type: Cell Culture Supernates
  104. Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation.
    Authors: Smith C, Damas JK, Otterdal K, ØIe E, Sandberg WJ, Yndestad A, Waehre T, Scholz H, Endresen K, Olofsson PS, Halvorsen B, Gullestad L, Froland SS, Hansson GK, Aukrust P
    J. Am. Coll. Cardiol., 2006;48(8):1591-9.
    Species: Human
    Sample Type: Cell Culture Supernates
  105. Regulated upon activation, normal T cell expressed and secreted (RANTES) and monocyte chemotactic protein 1 in follicular fluid accumulate differentially in patients with and without endometriosis undergoing in vitro fertilization.
    Authors: Schultze-Mosgau A, Agic A, Diedrich K, Hornung D
    Fertil. Steril., 2006;86(6):1616-20.
    Species: Human
    Sample Type: Serum
  106. Relationship of CSF leukocytosis to compartmentalized changes in MCP-1/CCL2 in the CSF of HIV-infected patients undergoing interruption of antiretroviral therapy.
    Authors: Monteiro de Almeida S, Letendre S, Zimmerman J, Kolakowski S, Lazzaretto D, McCutchan JA, Ellis R
    J. Neuroimmunol., 2006;179(1):180-5.
    Species: Human
    Sample Type: CSF
  107. Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities.
    Authors: Pang L, Nie M, Corbett L, Sutcliffe A, Knox AJ
    J. Immunol., 2006;176(6):3788-95.
    Species: Human
    Sample Type: Cell Culture Supernates
  108. RANTES and monocyte chemoattractant protein 1 as sensitive markers of disease activity in patients with juvenile rheumatoid arthritis: a six-year longitudinal study.
    Authors: Yao TC, Kuo ML, See LC, Ou LS, Lee WI, Chan CK, Huang JL
    Arthritis Rheum., 2006;54(8):2585-93.
    Species: Human
    Sample Type: Serum
  109. Exhaled breath condensate levels of 8-isoprostane, growth related oncogene alpha and monocyte chemoattractant protein-1 in patients with chronic obstructive pulmonary disease.
    Authors: Ko FW, Lau CY, Leung TF, Wong GW, Lam CW, Hui DS
    Respir Med, 2006;100(4):630-8.
    Species: Human
    Sample Type: Exhaled Breath Condensate (EBC)
  110. Changes in immune and glial markers in the CSF of patients with Complex Regional Pain Syndrome.
    Authors: Alexander GM, Perreault MJ, Reichenberger ER, Schwartzman RJ
    Brain Behav. Immun., 2006;21(5):668-76.
    Species: Human
    Sample Type: CSF
  111. Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis.
    Authors: Hsu YH, Li HH, Hsieh MY, Liu MF, Huang KY, Chin LS, Chen PC, Cheng HH, Chang MS
    Arthritis Rheum., 2006;54(9):2722-33.
    Species: Human
    Sample Type: Cell Culture Supernates
  112. CD16+ monocyte-derived macrophages activate resting T cells for HIV infection by producing CCR3 and CCR4 ligands.
    Authors: Ancuta P, Autissier P, Wurcel A, Zaman T, Stone D, Gabuzda D
    J. Immunol., 2006;176(10):5760-71.
    Species: Human
    Sample Type: Cell Culture Supernates
  113. No difference in the effects of clopidogrel and aspirin on inflammatory markers in patients with coronary heart disease.
    Authors: Solheim S, Pettersen AA, Arnesen H, Seljeflot I
    Thromb. Haemost., 2006;96(5):660-4.
    Species: Human
    Sample Type: Plasma
  114. Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2.
    Authors: Haukeland JW, Damas JK, Konopski Z, Loberg EM, Haaland T, Goverud I, Torjesen PA, Birkeland K, Bjoro K, Aukrust P
    J. Hepatol., 2006;44(6):1167-74.
    Species: Human
    Sample Type: Serum
  115. Comparison of serum levels of inflammatory markers in patients with coronary vasospasm without significant fixed coronary artery disease versus patients with stable angina pectoris and acute coronary syndromes with significant fixed coronary artery disease.
    Authors: Hung MJ, Cherng WJ, Cheng CW, Li LF
    Am. J. Cardiol., 2006;97(10):1429-34.
    Species: Human
    Sample Type: Serum
  116. Correlations between IL-4, IL-12 levels and CCL2, CCL5 levels in serum and cerebrospinal fluid of multiple sclerosis patients.
    Authors: Bartosik-Psujek H, Stelmasiak Z
    J Neural Transm, 2005;112(6):797-803.
    Species: Human
    Sample Type: Serum
  117. Simian human immunodeficiency virus-associated pneumonia correlates with increased expression of MCP-1, CXCL10, and viral RNA in the lungs of rhesus macaques.
    Authors: Sui Y, Li S, Pinson D, Adany I, Li Z, Villinger F, Narayan O, Buch S
    Am. J. Pathol., 2005;166(2):355-65.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Tissue Homogenates
  118. Markers of immune activation and viral load in HIV-associated sensory neuropathy.
    Authors: Schifitto G, McDermott MP, McArthur JC, Marder K, Sacktor N, McClernon DR, Conant K, Cohen B, Epstein LG, Kieburtz K, Kieburtz K
    Neurology, 2005;64(5):842-8.
    Species: Human
    Sample Type: CSF
  119. Endurance training reduces circulating inflammatory markers in persons at risk of coronary events: impact on plaque stabilization?
    Authors: Niessner A, Richter B, Penka M, Steiner S, Strasser B, Ziegler S, Heeb-Elze E, Zorn G, Leitner-Heinschink A, Niessner C, Wojta J, Huber K
    Atherosclerosis, 2005;186(1):160-5.
    Species: Human
    Sample Type: Plasma
  120. CCR5 expression and CC chemokine levels in idiopathic pulmonary fibrosis.
    Authors: Capelli A, Di Stefano A, Gnemmi I, Donner CF
    Eur. Respir. J., 2005;25(4):701-7.
    Species: Human
    Sample Type: BALF
  121. Interleukin-8, monocyte chemoattractant protein-1 and IL-10 in the vitreous fluid of patients with proliferative diabetic retinopathy.
    Authors: Hernandez C, Segura RM, Fonollosa A, Carrasco E, Francisco G, Simo R
    Diabet. Med., 2005;22(6):719-22.
    Species: Human
    Sample Type: Vitreous Humor
  122. Th2 predominance and CD8+ memory T cell depletion in patients with severe acute respiratory syndrome.
    Authors: Huang JL, Huang J, Duan ZH, Wei J, Min J, Luo XH, Li JG, Tan WP, Wu LZ, Liu RY, Li Y, Shao J, Huang BJ, Zeng YX, Huang W
    Microbes Infect., 2005;7(3):427-36.
    Species: Human
    Sample Type: Serum
  123. Messenger RNA expression of target genes in the urinary sediment of patients with chronic kidney diseases.
    Authors: Szeto CC, Chan RW, Lai KB, Szeto CY, Chow KM, Li PK, Lai FM
    Nephrol. Dial. Transplant., 2005;20(1):105-13.
    Species: Human
    Sample Type: Urine
  124. Th2 predominance and CD8+ memory T cell depletion in patients with severe acute respiratory syndrome.
    Authors: Huang JL, Huang J, Duan ZH, Wei J, Min J, Luo XH, Li JG, Tan WP, Wu LZ, Liu RY, Li Y, Shao J, Huang BJ, Zeng YX, Huang W
    Microbes Infect., 2005;7(3):427-36.
    Species: Human
    Sample Type: Serum
  125. Cerebrospinal fluid markers that predict SIV CNS disease.
    Authors: Mankowski JL, Queen SE, Clements JE, Zink MC
    J. Neuroimmunol., 2004;157(1):66-70.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Plasma
  126. Differential macrophage infiltration in early and advanced endometriosis and adjacent peritoneum.
    Authors: Khan KN, Masuzaki H, Fujishita A, Kitajima M, Sekine I, Ishimaru T
    Fertil. Steril., 2004;81(3):652-61.
    Species: Human
    Sample Type: Peritoneal Fluid
  127. Alterations in expression of monocyte chemotactic protein-1 in the simian immunodeficiency virus model of disseminated Mycobacterium avium complex.
    Authors: Hendricks EE, Lin KC, Boisvert K, Pauley D, Mansfield KG
    J. Infect. Dis., 2004;189(9):1714-20.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Cell Culture Supernates
  128. Oxidative stress and renal injury with intravenous iron in patients with chronic kidney disease.
    Authors: Vasavada N, Sachs NG, Chase S
    Kidney Int., 2004;65(6):2279-89.
    Species: Human
    Sample Type: Urine
  129. Effects of contrast media on porcine bone marrow-derived mononuclear cells and calf myoblast viability and secretion of VEGF and MCP-1.
    Authors: Baffour R, Pakala R, Hellinga D, Seabron R, Fournadjiev J, Wolfram R, Okubagzi P, Epstein SE, Waksman R
    Catheter Cardiovasc Interv, 2004;62(4):476-81.
    Species: Porcine
    Sample Type: Cell Culture Supernates
  130. Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2.
    Authors: Metelitsa LS, Wu HW, Wang H, Yang Y, Warsi Z, Asgharzadeh S, Groshen S, Wilson SB, Seeger RC
    J. Exp. Med., 2004;199(9):1213-21.
    Species: Human
    Sample Type: Cell Culture Supernates
  131. Monocyte chemoattractant protein-1 and interleukin-8 levels in children with acute poststreptococcal glomerulonephritis.
    Authors: Besbas N, Ozaltin F, Catal F, Ozen S, Topaloglu R, Bakkaloglu A
    Pediatr. Nephrol., 2004;19(8):864-8.
    Species: Human
    Sample Type: Urine
  132. CXCR3 and CCR5 positive T-cell recruitment in acute human renal allograft rejection.
    Authors: Panzer U, Reinking RR, Steinmetz OM, Zahner G, Sudbeck U, Fehr S, Pfalzer B, Schneider A, Thaiss F, Mack M, Conrad S, Huland H, Helmchen U, Stahl RA
    Transplantation, 2004;78(9):1341-50.
    Species: Human
    Sample Type: Urine
  133. CD8+ cell depletion amplifies the acute retroviral syndrome.
    Authors: Madden LJ, Zandonatti MA, Flynn CT, Taffe MA, Marcondes MC, Schmitz JE, Reimann KA, Henriksen SJ, Fox HS
    J. Neurovirol., 2004;10(0):58-66.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: CSF
  134. The effect of inflammatory cytokines on secretion of macrophage colony-stimulating factor and monocyte chemoattractant protein-1 in human granulosa cells.
    Authors: Kawano Y, Fukuda J, Itoh H, Takai N, Nasu K, Miyakawa I
    Am. J. Reprod. Immunol., 2004;52(2):124-8.
    Species: Human
    Sample Type: Follicular Fluid
  135. CXC-chemokine stimulation of neutrophils correlates with plasma levels of myeloperoxidase and lactoferrin and contributes to clinical outcome after pediatric cardiac surgery.
    Authors: Gessler P, Pretre R, Hohl V, Rousson V, Fischer J, Dahinden C
    Shock, 2004;22(6):513-20.
    Species: Human
    Sample Type: Plasma
  136. The monocyte chemotactic protein-1 -2578G allele is associated with elevated MCP-1 concentrations in cerebrospinal fluid.
    Authors: Letendre S, Marquie-Beck J, Singh KK, de Almeida S, Zimmerman J, Spector SA, Grant I, Ellis R
    J. Neuroimmunol., 2004;157(1):193-6.
    Species: Human
    Sample Type: Plasma
  137. Proinflammatory effects of oxidative stress in chronic kidney disease: role of additional angiotensin II blockade.
    Authors: Agarwal R
    Am. J. Physiol. Renal Physiol., 2003;284(4):F863-9.
    Species: Human
    Sample Type: Urine
  138. Helper T-lymphocyte-related chemokines in healthy newborns.
    Authors: Leung TF, Ng PC, Tam WH, Li CY, Wong E, Ma TP, Lam CW, Fok TF
    Pediatr. Res., 2003;55(2):334-8.
    Species: Human
    Sample Type: Serum
  139. Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection.
    Authors: Geisbert TW, Hensley LE, Larsen T, Young HA, Reed DS, Geisbert JB, Scott DP, Kagan E, Jahrling PB, Davis KJ
    Am. J. Pathol., 2003;163(6):2347-70.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Type: Serum
  140. Neuropathogenesis of lentiviral infection in macaques: roles of CXCR4 and CCR5 viruses and interleukin-4 in enhancing monocyte chemoattractant protein-1 production in macrophages.
    Authors: Hicks A, Potula R, Sui YJ, Villinger F, Pinson D, Adany I, Li Z, Long C, Cheney P, Marcario J, Novembre F, Mueller N, Kumar A, Major E, Narayan O, Buch S
    Am. J. Pathol., 2002;161(3):813-22.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Cell Culture Supernates
  141. TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion.
    Authors: Ciesielski CJ, Andreakos E, Foxwell BM, Feldmann M
    Eur. J. Immunol., 2002;32(7):2037-45.
    Species: Human
    Sample Type: Cell Culture Supernates
  142. Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites.
    Authors: Milliken D, Scotton C, Raju S, Balkwill F, Wilson J
    Clin. Cancer Res., 2002;8(4):1108-14.
    Species: Human
    Sample Type: Plasma
  143. Fibrinogen induces chemotactic activity in endothelial cells.
    Authors: Seeger FH, Blessing E, Gu L, Bornhold R, Denger S, Kreuzer J
    Acta Physiol. Scand., 2002;176(2):109-15.
    Species: Porcine
    Sample Type: Cell Culture Supernates
  144. Correlates of independent HIV-1 replication in the CNS and of its control by antiretrovirals.
    Authors: De Luca A, Ciancio BC, Larussa D, Murri R, Cingolani A, Rizzo MG, Giancola ML, Ammassari A, Ortona L
    Neurology, 2002;59(3):342-7.
    Species: Human
    Sample Type: CSF
  145. CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor.
    Authors: Honczarenko M, Le Y, Glodek AM, Silberstein LE
    Blood, 2002;100(7):2321-9.
    Species: Human
    Sample Type: Cell Culture Supernates
  146. Impact of NNRTI compared to PI-based highly active antiretroviral therapy on CCR5 receptor expression, beta-chemokines and IL-16 secretion in HIV-1 infection.
    Authors: Burton CT, Hardy GA, Sullivan AK, Nelson MR, Gazzard B, Gotch FM, Imami N
    Clin. Exp. Immunol., 2002;130(2):286-92.
    Species: Human
    Sample Type: Plasma
  147. Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental myocardial ischemia.
    Authors: Fuchs S, Baffour R, Zhou YF, Shou M, Pierre A, Tio FO, Weissman NJ, Leon MB, Epstein SE, Kornowski R
    J. Am. Coll. Cardiol., 2001;37(6):1726-32.
    Species: Porcine
    Sample Type: Cell Culture Supernates
  148. Increased macrophage chemoattractant protein-1 in cerebrospinal fluid precedes and predicts simian immunodeficiency virus encephalitis.
    Authors: Zink MC, Coleman GD, Mankowski JL, Adams RJ, Tarwater PM, Fox K, Clements JE
    J. Infect. Dis., 2001;184(8):1015-21.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: CSF
  149. Up-regulation of beta-chemokines and down-modulation of CCR5 co-receptors inhibit simian immunodeficiency virus transmission in non-human primates.
    Authors: Lehner T, Wang Y, Cranage M, Tao L, Mitchell E, Bravery C, Doyle C, Pratt K, Hall G, Dennis M, Villinger L, Bergmeier L
    Immunology, 2000;99(4):569-77.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Cell Culture Supernates
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Average Rating: 4.8 (Based on 5 reviews)

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 Human CCL2/MCP-1 Quantikine ELISA Kit DCP00 Array DCP00
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Excellent
  Anonymous 05/01/2018
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 Human CCL2/MCP-1 Quantikine ELISA Kit DCP00
: Human CCL2/MCP-1 Quantikine ELISA Kit [DCP00].

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Sample Tested Cell Culture Media
 Human CCL2/MCP-1 Quantikine ELISA Kit DCP00 Array DCP00
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Excellent
  Anonymous 12/04/2017
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 Human CCL2/MCP-1 Quantikine ELISA Kit DCP00
: Human CCL2/MCP-1 Quantikine ELISA Kit [DCP00].

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Sample Tested Primary human lunf fibroblast,Primary human lung fibroblast

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Other Experimental Details This result has been published in the PlosONE journal: 10.1371/journal.pone.0058258
 Human CCL2/MCP-1 Quantikine ELISA Kit DCP00 Array DCP00
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Excellent
  Anonymous 08/18/2017
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 Human CCL2/MCP-1 Quantikine ELISA Kit DCP00
: Human CCL2/MCP-1 Quantikine ELISA Kit [DCP00].

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Sample Tested Human tissue

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Other Experimental Details Very decent price and perfect customer support
 Human CCL2/MCP-1 Quantikine ELISA Kit DCP00 Array DCP00
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Excellent
  Anonymous 07/24/2017
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 Human CCL2/MCP-1 Quantikine ELISA Kit DCP00
: Human CCL2/MCP-1 Quantikine ELISA Kit [DCP00].

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Sample Tested cell culture supernatants

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Other Experimental Details cell culture supernatants were diluted 1:5
 Human CCL2/MCP-1 Quantikine ELISA Kit DCP00 Array DCP00
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Very Good
  Anonymous 12/14/2016
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 Human CCL2/MCP-1 Quantikine ELISA Kit DCP00
: Human CCL2/MCP-1 Quantikine ELISA Kit [DCP00].

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Sample Tested EDTA Plasma

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Other Experimental Details MCP-1 concentrations were measured in plasma of HIV+ subjects on HAART and in healthy controls. Blood was collected in EDTA-tubes and plasma separated by centrifugation at 2000rpm for 20 minutes at 20oC. Plasma was diluted 1:2 before use in the assay.Figure Legend for Figure:a) Standard curve for MCP-1 from which values were extrapolated.b) MCP-1 concentrations in plasma of HIV+ and HIV- subjects. Values are expressed as pg/ml and are significantly elevated in HIV+?ART group. Analyses done using non parametric unpaired Mann Whitney U-test.

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