Human CD-M6PR Lumenal Domain Biotinylated Antibody

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Product Details
Supplemental Products

Human CD-M6PR Lumenal Domain Biotinylated Antibody Summary

Species Reactivity
Detects human CD-M6PR Lumenal Domain in Western blots. In Western blots, approximately 40% cross‑reactivity with recombinant mouse CD-M6PR is observed.
Polyclonal Goat IgG
Antigen Affinity-purified
Mouse myeloma cell line NS0-derived recombinant human CD-M6PR Lumenal Domain
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Human CD-M6PR Lumenal Domain

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

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Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CD-M6PR

The CD-M6PR (cation-dependent mannose 6-phosphate receptor; also CD-MPR) is a 44‑46 kDa member of the P-type lectin family of proteins. It is ubiquitously expressed, found internally, and transports newly formed mannose 6-phosphate bearing acid hydrolases from the secretory pathway to acidified lysosomes. Mature human CD-M6PR is a type I transmembrane glycoprotein that is 251 amino acids (aa) in length. It functions as a homodimer, and contains a 159 aa luminal region (aa 27‑185) plus a 67 aa cytoplasmic domain. The aa residues Gln66, Arg111, Glu133 and Tyr143 recognize carbohydrate; Asp103 interacts with divalent cation (Mn2+), increasing ligand affinity and receptor oligomerization. Over aa 27‑184, human CD-M6PR shares 90% aa identity with mouse CD-M6PR.

Long Name
Cation Dependent Mannose-6-Phosphate Receptor 46 kDa
Entrez Gene IDs
4074 (Human); 17113 (Mouse); 312689 (Rat)
Alternate Names
000 Man6PR; 46 kDa mannose 6-phosphate receptor; 46-kDa mannose 6-phosphate receptor; cation-dependent mannose-6-phosphate receptor; CD Man-6-P receptor; CDM6PR; CD-M6PR; CD-MPR; FLJ32994; M6PR; mannose-6-phosphate receptor (cation dependent); MPR 46; MPR46; MPRD; Mr 46; SMPR

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