Human CS Citrate Synthase Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB11583N Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB11583N-100UG

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Human CS Citrate Synthase Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects a synthetic peptide corresponding to residues near amino acid 400 of human CS protein in Direct ELISA.
Source
Monoclonal Mouse IgG2a Clone # 1081813
Purification
Protein A or G purified
Immunogen
Synthetic Peptide
Accession # O75390
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CS Citrate Synthase

Citrate Synthase (CS) is a 52kDa enzyme found in nearly all cells capable of oxidative metabolism. This enzyme is the first step of the tricarboxylic acid (TCA) cycle and is found in the mitochondrial matrix.  Citrate Synthase is commonly used as a marker for the presence of intact mitochondria. Loss of CS facilitates cytosolic glycolysis and results in epithelial-mesenchymal transition (EMT) and tumor malignancy.

Long Name
CS Citrate Synthase
Entrez Gene IDs
1431 (Human); 12974 (Mouse); 170587 (Rat)
Alternate Names
citrate (Si)-synthase; citrate synthase; citrate synthase, mitochondrial; CS Citrate Synthase; EC 2.3.3; EC 2.3.3.1

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