Human CS Citrate Synthase Alexa Fluor® 700-conjugated Antibody Summary
Accession # O75390
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
Background: CS Citrate Synthase
Citrate Synthase (CS) is a 52kDa enzyme found in nearly all cells capable of oxidative metabolism. This enzyme is the first step of the tricarboxylic acid (TCA) cycle and is found in the mitochondrial matrix. Citrate Synthase is commonly used as a marker for the presence of intact mitochondria. Loss of CS facilitates cytosolic glycolysis and results in epithelial-mesenchymal transition (EMT) and tumor malignancy.
Product Datasheets
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