Human CXCL1/2/3/GRO Pan Specific Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB276S Datasheet / COA / SDS

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FAB276S-100UG

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All CXCL3/GRO gamma/CINC-2/DCIP-1 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CXCL1/2/3/GRO Pan Specific Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human CXCL1/2/3 in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG1 Clone # 31716

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human CXCL2
Ala35-Asn107
Accession # P19875

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Neutralization

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CXCL3/GRO gamma/CINC-2/DCIP-1

CXCL1, CXCL2 (MIP-2 alpha ), and CXCL3 (MIP-2 beta ) are members of the alpha (C-X-C) subfamily of chemokines and are now designated GRO alpha, GRO beta, and GRO gamma, respectively. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators.

Entrez Gene IDs

2921 (Human); 330122 (Mouse); 171551 (Rat)

Alternate Names

chemokine (C-X-C motif) ligand 3; CINC-2; CINC-2b; C-X-C motif chemokine 3; CXCL3; Dcip1; Gm1960; GRO gamma; GRO3 oncogene; GRO3; GROG; GRO-gamma; GRO-gamma(1-73); Growth-regulated protein gamma; Macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma; MGSA gamma; MIP2B; MIP-2b; MIP2-beta; SCYB3