Detection of CXCR1/IL‑8 RA in Human Blood Granulocytes by Flow Cytometry. |
Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR1/IL‑8 RA Alexa Fluor® 700-conjugated Monoclonal Antibody (Catalog # FAB330N, filled histogram) or isotype control antibody(Catalog # IC003N, open histogram). View our protocol for Staining Membrane-associated Proteins.
The human C-X-C chemokine IL-8 is a potent neutrophil chemotactic and activating factor. Two distinct G protein-linked cell surface receptors, known as IL-8 RA (type I or CXCR1) and IL-8 RB (type II or CXCR2), can interact with the IL-8 molecule. These two receptors share 77% amino acid homology. CXCR1 expression has been documented on neutrophils, monocytes, and a small population of T cells.
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