Human DEC-205/CD205 Alexa Fluor® 532-conjugated Antibody

Catalog #: FAB20471X Datasheet / COA / SDS

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FAB20471X-100UG

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Human DEC-205/CD205 Alexa Fluor® 532-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human DEC‑205/CD205 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse DEC-205 is observed.

Source

Monoclonal Mouse IgG1 Clone # 523218

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human DECâ€‘205/CD205
Cys216-Cys501
Accession # O60449

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 532 (Excitation= 534 nm, Emission= 553 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: DEC-205/CD205

DEC-205, also known as CD205 and lymphocyte antigen 75 (Ly 75), is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. The extracellular region of DEC-205 contains ten C-type lectin-like domains, a fibronectin type II domain and a ricin B-type lectin domain. DEC-205 functions as an endocytic receptor for antigens. The recombinant protein used to generate the anti-human DEC-205 antibody contains the first two C-type lectin domains.

Entrez Gene IDs

4065 (Human); 17076 (Mouse)

Alternate Names

CD205; CLEC13B; C-type lectin domain family 13 member B; DEC205; DEC-205; GP200-MR6; Ly75; Ly-75; Lymphocyte antigen 75