Human Fc epsilon RI alpha (AAH15195) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Human Fc epsilon RI alpha (AAH15195) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: Fc epsilon RI alpha

Fc epsilon RI alpha is a transmembrane protein that associates with beta and gamma subunits to form the high affinity IgE receptor on basophils and mast cells. Cellular activation by IgE/Fc epsilon RI crosslinking causes degranulation, releasing histamine, leukotrienes, prostaglandins, and other mediators of immediate type and late phase allergic reactions. Fc epsilon RI on human antigen presenting cells mediates uptake and processing of allergens for presentation by class II MHC. Fc epsilon RI expression on human DC and Langerhans cells is upregulated during allergic reactions (atopy) and correlates with serum IgE concentration.

Long Name
Fc epsilon Receptor I alpha
Entrez Gene IDs
2205 (Human); 14125 (Mouse); 25047 (Rat)
Alternate Names
Fc epsilon RI alpha; FCE1A; FCE1A;fcepsilonri;FCER1A;FcERI;Fcr-5; FCER1A; FcERI; FceRIa


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