Fc epsilon RI alpha is a transmembrane protein that associates with beta and gamma subunits to form the high affinity IgE receptor on basophils and mast cells. Cellular activation by IgE/Fc epsilon RI crosslinking causes degranulation, releasing histamine, leukotrienes, prostaglandins, and other mediators of immediate‑type and late‑phase allergic reactions. Fc epsilon RI on human antigen presenting cells mediates uptake and processing of allergens for presentation by class II MHC. Fc epsilon RI expression on human DC and Langerhans cells is upregulated during allergic reactions (atopy) and correlates with serum IgE concentration.
Human Fc epsilon RI alpha (AAH15195) VersaClone cDNA
R&D Systems | Catalog # RDC1775
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Fc epsilon RI alpha
Long Name
Fc epsilon Receptor I alpha
Alternate Names
FCE1A, FCER1A, FcERI, FceRIa
Gene Symbol
FCER1A
UniProt
Additional Fc epsilon RI alpha Products
Product Documents for Human Fc epsilon RI alpha (AAH15195) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human Fc epsilon RI alpha (AAH15195) VersaClone cDNA
For research use only
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