Human FPR1 Alexa Fluor® 750-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB3744S-100UG

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Human FPR1 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human FPR1. Stains human FPR1-transfected cells but not irrelevant transfectants.
Source
Monoclonal Mouse IgG2a Clone # 350418
Immunogen
HEK293 human embryonic kidney cell line transfected with human FPR1
Met1-Lys350
Accession # NP_002020
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
Human whole blood monocytes

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: FPR1

FPR1, FPRL1, and FPRL2 constitute a group of 7-transmembrane segment chemotactic receptors that are expressed on phagocytes. FPR1 binding of bacterial N‑formyl‑methionyl peptides draws neutrophils to sites of infection and promotes degranulation. Human and mouse FPR1 share 73% amino acid sequence identity.

Long Name
Formyl Peptide Receptor 1
Entrez Gene IDs
2357 (Human); 14293 (Mouse); 292409 (Rat)
Alternate Names
fMet-Leu-Phe receptor; fMLF-R; fMLP receptor; FMLP; formyl peptide receptor 1; FPR1; FPRfMet-Leu-Phe receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor

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Product Specific Notices


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

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