Detection of FPR1 in Human Monocytes by Flow Cytometry. Human monocytes were stained with Mouse Anti-Human FPR1 PE‑conjugated Monoclonal Antibody (Catalog # FAB3744P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
FPR1, FPRL1, and FPRL2 constitute a group of 7-transmembrane segment chemotactic receptors that are expressed on phagocytes. FPR1 binding of bacterial N‑formyl‑methionyl peptides draws neutrophils to sites of infection and promotes degranulation. In addition, a novel chemokine-like molecule, FAM19A4, has also been shown to bind to FPR1. Human and mouse FPR1 share 73% amino acid sequence identity.
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