Human FPR1 PE-conjugated Antibody

(3 citations)   
  • Species Reactivity
  • Specificity
    Detects human FPR1. Stains human FPR1-transfected cells but not irrelevant transfectants.
  • Source
    Monoclonal Mouse IgG2A Clone # 350418
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    HEK293 human embryonic kidney cell line transfected with human FPR1
    Accession # NP_002020
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of FPR1 in Human Monocytes by Flow Cytometry. Human monocytes were stained with Mouse Anti-Human FPR1 PE‑conjugated Monoclonal Antibody (Catalog # FAB3744P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: FPR1
FPR1, FPRL1, and FPRL2 constitute a group of 7-transmembrane segment chemotactic receptors that are expressed on phagocytes. FPR1 binding of bacterial N‑formyl‑methionyl peptides draws neutrophils to sites of infection and promotes degranulation. In addition, a novel chemokine-like molecule, FAM19A4, has also been shown to bind to FPR1.  Human and mouse FPR1 share 73% amino acid sequence identity.
  • Long Name:
    Formyl Peptide Receptor 1
  • Entrez Gene IDs:
    2357 (Human); 14293 (Mouse); 292409 (Rat)
  • Alternate Names:
    fMet-Leu-Phe receptor; fMLF-R; fMLP receptor; FMLP; formyl peptide receptor 1; FPRfMet-Leu-Phe receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor
Related Research Areas

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

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Sample Type
  1. The leukocyte chemotactic receptor FPR1 is functionally expressed on human lens epithelial cells.
    Authors: Schneider, Erich H, Weaver, Joseph D, Gaur, Sonia S, Tripathi, Brajendr, Jesaitis, Algirdas, Zelenka, Peggy S, Gao, Ji-Liang, Murphy, Philip M
    J Biol Chem, 2012;287(48):40779-92.
    Species: Human
    Sample Type: whole cells
    Application: Flow
  2. Regulation of the formyl peptide receptor 1 (FPR1) gene in primary human macrophages.
    Authors: Gemperle C, Schmid M, Herova M, Marti-Jaun J, Wuest S, Loretz C, Hersberger M
    PLoS ONE, 2012;7(11):e50195.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  3. Severe congenital neutropenia resulting from G6PC3 deficiency with increased neutrophil CXCR4 expression and myelokathexis.
    Authors: McDermott DH, De Ravin SS, Jun HS
    Blood, 2010;116(15):2793-802.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
Isotype Controls
Description Application Cat# Citations Images  

Mouse IgG2A PE-conjugated Antibody

Ctrl IC003P 10  
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Staining Reagents
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Flow Cytometry Staining Buffer (1X)

Flow FC001 3
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Flow Cytometry Mouse Lyse Buffer (10X)

Flow FC003 1
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Flow Cytometry Human Lyse Buffer (10X)

Flow FC002 1
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