Human Glucagon R/GCGR (NP_000151) VersaClone cDNA Summary
Background: Glucagon R/GCGR
Glucagon R (GCGR) is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of GCGR is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in GCGR are a cause of non-insulin-dependent diabetes mellitus.
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