Human Glut2 Alexa Fluor® 405-conjugated Antibody Summary
Accession # P11168
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
Glut2 belongs to the facilitative glucose transporter protein family that comprises 13 members. It is an integral membrane protein with 12 transmembrane domains. Glut2 is expressed predominantly in liver, intestine, kidney, and pancreatic beta-cells. It is a low-affinity glucose transporter that has been suggested to function as a glucose sensor in pancreatic beta-cells and facilitate either glucose uptake or efflux from cells depending on the nutritional state (1).
- Olson, A.L. and J.E. Pessin (1996) Annu. Rev. Nut. 16:235.
- Mahraoui, L. et al. (1994) J. Biochem. 298:629.
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