Human HB-EGF Quantikine ELISA Kit Summary
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Cell Culture Supernates, Serum, EDTA Plasma, Platelet-poor EDTA Plasma, Heparin Plasma, Platelet-poor Heparin Plasma, Saliva, Urine, Human Milk
|Intra-Assay Precision||Inter-Assay Precision|
The recovery of human HB-EGF spiked to levels throughout the range of the assay in various matrices was evaluated.
|Sample Type||Average % Recovery||Range %|
|Cell Culture Media (n=4)||120||113-125|
|EDTA Plasma (n=4)||99||83-114|
|Heparin Plasma (n=4)||84||75-96|
|Platelet-poor EDTA Plasma (n=4)||101||84-119|
|Platelet-poor Heparin Plasma (n=4)||98||75-111|
Human HB-EGF ELISA Standard Curve
Preparation and Storage
HB-EGF (Heparin-Binding EGF-like growth factor), also known as DTR, is produced by bronchial epithelium, visceral and vascular smooth muscle, CD4+ T cells, cardiac muscle, glomerular podocytes, keratinocytes, and IL-10-secreting regulatory macrophages. It activates both the EGF R/ErbB1 and ErbB4 receptors and has been linked to many cellular processes including proliferation, apoptosis, cell migration/invasion, differentiation, morphogenesis, and development. HB-EGF is also involved in several aspects of cancer development and progression.
Citations for Human HB-EGF Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 3
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Serum Concentration of Selected Angiogenesis-Related Molecules Differs among Molecular Subtypes, Body Mass Index and Menopausal Status in Breast Cancer Patients
Authors: D Balalis, D Tsakogiann, E Kalogera, S Kokkali, E Tripodaki, A Ardavanis, D Manatakis, D Dimas, N Koufopoulo, F Fostira, D Korkolis, I Misitzis, N Vassos, C Spiliopoul, D Vlachodimi, G Bletsa, N Arkadopoul
Sample Types: Serum
Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway
Authors: JJ Zhang, CX Cao, LL Wan, W Zhang, ZJ Liu, JL Wang, Q Guo, H Tang
World Journal of Gastroenterology, 2022;28(17):1781-1797.
Sample Types: Cell Culture Supernates
Serum Amphiregulin and Heparin-Binding Epidermal Growth Factor as Biomarkers in Patients with Idiopathic Inflammatory Myopathy
Authors: N Hanata, Y Nagafuchi, Y Sugimori, S Kobayashi, Y Tsuchida, Y Iwasaki, H Shoda, K Fujio
Journal of Clinical Medicine, 2021;10(16):.
Sample Types: Serum
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