Home / HLA-DRB1 / Human HLA-DRB1 Alexa Fluor® 594-conjugated Antibody

Human HLA-DRB1 Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB11640T Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB11640T-100UG
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human HLA-DRB1 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects a synthetic peptide specific for human HLA-DRB1 around amino acid 45 in Direct ELISA.
Source
Monoclonal Mouse IgG2b Clone # 1091354
Purification
Protein A or G purified
Immunogen
Synthetic Peptide
Accession # P01911
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: HLA-DRB1

HLA-DRB1 is an HLA class II histocompatibility antigen.  It is part of a heterodimer consisting of an alpha (DRA) and a beta chain (DRB) which are both anchored in the membrane.  Class II molecules are constitutively expressed in professional APC's. HLA-II is an important immune system protein that plays a role in tumor antigen presentation, immune response, and immune surveillance.  HLA-DRB1 presents antigenic peptides to HLA-DRB1-restricted CD4+ T-cells. Aberrant expression of HLA-II is closely related to the pathogenesis of tumors.

Long Name
Major histocompatibility complex, class II, DR beta 1
Entrez Gene IDs
3123 (Human)
Alternate Names
Clone P2-beta-3; DR1; DR-1; DR12; DR-12; DR13; DR-13; DR14; DR-14; DR16; DR-16; DR4; DR-4; DR5; DR-5; DR7; DR-7; DR8; DR-8; DR9; DR-9; DRB1; DRw10; DRw11; DRw8; DW2.2/DR2.2; FLJ75017; FLJ76359; HLA class II antigen beta chain; HLA class II histocompatibility antigen, DR-1 beta chain; HLA-DR1B; HLA-DRB; HLA-DRB1; HLA-DRB1*; HLA-DRB2; HLA-DR-beta 1; human leucocyte antigen DRB1; leucocyte antigen DR beta 1 chain; leucocyte antigen DRB1; lymphocyte antigen DRB1; major histocompatibility complex, class II, DR beta 1; MHC class II antigen DRB1*1; MHC class II antigen DRB1*10; MHC class II antigen DRB1*11; MHC class II antigen DRB1*12; MHC class II antigen DRB1*13; MHC class II antigen DRB1*14; MHC class II antigen DRB1*15; MHC class II antigen DRB1*16; MHC class II antigen DRB1*3; MHC class II antigen DRB1*4; MHC class II antigen DRB1*7; MHC class II antigen DRB1*8; MHC class II antigen DRB1*9; MHC class II antigen HLA-DR13; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta; SS1

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