Human IL-38/IL-1F10 Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB24271R Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB24271R-100UG

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Human IL-38/IL-1F10 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human IL‑38/IL‑1F10 in direct ELISAs.
Source
Monoclonal Mouse IgG3 Clone # 892257
Purification
Protein A or G purified
Immunogen
E. coli-derived human IL‑38/IL‑1F10
Ser3-Trp152
Accession # Q8WWZ1
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration
Sample
ELISA
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: IL-38/IL-1F10

Human IL-38, previously called IL-1F10 or IL-1HY2, is a secreted cytokine belonging to the IL-1 family. It is synthesized as a 152 amino acid mature protein that lacks an identifiable signal sequence. It binds to soluble IL-1 RI. Human IL-38/IL-1F10 shares 82% aa sequence identity with mouse  IL-38/IL-1F10. Human  IL-38/IL-1F10 also shares 39% and 27% aa sequence identity with IL-1ra/IL-1F3 and IL-1 beta /IL-1F2, respectively.

Long Name
Interleukin 1 Family Member 10
Entrez Gene IDs
84639 (Human); 215274 (Mouse); 102125744 (Cynomolgus Monkey)
Alternate Names
FIL1- theta; FKSG75; IL1F10; IL-1HY2; IL38; IL-38; interleukin 1 family, member 10 (theta); UNQ6119/PRO20041

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