Human Integrin alpha 5/CD49e Alexa Fluor® 647-conjugated Antibody Summary
Accession # P08648
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of Integrin alpha 5/CD49e in K562 Human Cell Line by Flow Cytometry. K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human Integrin alpha 5/CD49e Alexa Fluor® 647-conjugated Monoclonal Antibody (Catalog # FAB1864R, filled histogram) or isotype control antibody (Catalog # IC002R, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Integrin alpha 5/CD49e
The Integrin alpha 5 subunit, also called CD49e, associates with the Integrin beta 1 subunit (CD29) to form the VLA-5 complex. It functions as a receptor for fibronectin and is expressed on fibroblasts, endothelial cells, epithelial cells, platelets and some melanoma cell lines (1, 2).
- Springer, T.A. et al. (1982) Immunol. Rev. 68:171.
- Te Velde, A. et al. (1988) J. Immunol. 140:1548.
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