Human Integrin  alpha V beta 5 PE-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB2528P
Human Integrin  alpha V beta 5 PE-conjugated Antibody in Data
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Product Details
Citations (1)
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Human Integrin  alpha V beta 5 PE-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human Integrin alpha V beta 5. Recognizes the human Integrin alpha V beta 5 heterodimer and does not recognize the alpha V subunit in association with any other beta subunits.
Source
Monoclonal Mouse IgG1 Clone # P5H9
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
HT1080 human fibrosarcoma cell line
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Flow Cytometry Detection of Integrin  alpha V beta 5 in MCF‑7 Human Cell Line by Flow Cytometry. View Larger

Detection of Integrin alpha V beta 5 in MCF‑7 Human Cell Line by Flow Cytometry. MCF-7 human breast cancer cell line was stained with Mouse Anti-Human Integrin aV beta 5 PE-conjugated Monoclonal Antibody (Catalog # FAB2528P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: Integrin alpha V beta 5

Integrins are heterodimeric receptors comprised of an alpha and a beta subunit. Integrin alpha V (CD51) associates with several different beta subunits, but Integrin beta 5 associates exclusively with the alpha V subunit. Integrin alpha V beta 5, also known as Integrin alpha V beta S and Integrin alpha V beta 3B, is a transmembrane heterodimeric protein that functions as a receptor for Vitronectin. It is expressed on hepatoma cells, fibroblasts and carcinoma cells.

Entrez Gene IDs
3685 (Human)
Alternate Names
CD51; Integrin alpha V beta 5; integrin subunit alpha V; ITGAV; MSK8; VNRA; VTNR

Product Datasheets

Citation for Human Integrin  alpha V beta 5 PE-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Development of novel AAV serotype 6 based vectors with selective tropism for human cancer cells.
    Authors: Sayroo R, Nolasco D, Yin Z, Colon-Cortes Y, Pandya M, Ling C, Aslanidi G
    Gene Ther, 2016;23(1):18-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

FAQs

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Reviews for Human Integrin  alpha V beta 5 PE-conjugated Antibody

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Human Integrin  alpha V beta 5 PE-conjugated Antibody
By Anonymous on 08/01/2016
Application: Flow Sample Tested: Bone marrow cells Species: Human