Human Integrin  beta 3/CD61 APC-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB2266A
Detection of Integrin  beta 3/CD61 in Human Peripheral Blood Monocytes by Flow Cytometry.
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Citations (1)
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Human Integrin  beta 3/CD61 APC-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human Integrin  beta 3/CD61 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human Integrin  beta 1, beta 2, recombinant mouse Integrin beta 4, or beta 6 is observed.
Source
Monoclonal Mouse IgG2A Clone # 256809
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Integrin beta 3/CD61
Gly27-Asp718
Accession # P05106
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of Integrin  beta 3/CD61 antibody in Human Peripheral Blood Monocytes antibody by Flow Cytometry. View Larger

Detection of Integrin beta 3/CD61 in Human Peripheral Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human Integrin beta 3/CD61 APC-conjugated Monoclonal Antibody (Catalog # FAB2266A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: Integrin beta 3/CD61

Integrin beta 3, also called CD61, associates with the Integrin alpha IIb or alpha V subunits to form heterodimeric receptors for collagens, fibronectin, vitronectin, fibrinogen, Von willebrand factor or thrombospondin. alpha IIb/ beta 3, also known as GPIIb IIIa (Glycoprotein IIb-IIIa), is expressed on platelets. alpha V/ beta 3, also known as vitronectin receptor, is expressed on endothelial cells, some B cells, platelets and monocytes.

Entrez Gene IDs
3690 (Human); 16416 (Mouse); 29302 (Rat); 102117791 (Cynomolgus Monkey)
Alternate Names
CD61 antigen; CD61; GP3A; GP3Aplatelet glycoprotein IIIa; GPIIIA; GPIIIaintegrin beta-3; INGRB3; Integrin beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITG B3; ITGB3; Platelet membrane glycoprotein IIIa

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Citation for Human Integrin  beta 3/CD61 APC-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Negative regulation of osteoclast precursor differentiation by CD11b and beta2 integrin-B-cell lymphoma 6 signaling.
    Authors: Park-Min K, Lee E, Moskowitz N, Lim E, Lee S, Lorenzo J, Huang C, Melnick A, Purdue P, Goldring S, Ivashkiv L
    J Bone Miner Res, 2013-01-01;28(1):135-49.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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