Human IRAK1 Alexa Fluor® 405-conjugated Antibody

Catalog #: AF4048V Datasheet / COA / SDS

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AF4048V-100UG

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Human IRAK1 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human IRAK1 in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human (rh) IRAK2 and rhIRAK4 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human IRAK1
Met1-Ser693
Accession # AAH54000

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: IRAK1

IL-1 receptor-associated kinases (IRAKs) are serine/threonine kinases that regulate signaling from Toll-like receptor (TLR) and IL-1 receptor family members. Four human IRAKs have been identified: IRAK1, IRAK2, IRAK-M, and IRAK4. All IRAKs are multidomain proteins, containing a conserved N-terminal death domain as well as a central kinase domain that is only active in IRAK1 and IRAK4.

Long Name

Interleukin-1 Receptor-Associated Kinase 1

Entrez Gene IDs

3654 (Human); 16179 (Mouse); 363520 (Rat)

Alternate Names

EC 2.7.11; EC 2.7.11.1; Il1rak; interleukin-1 receptor-associated kinase 1; IRAK1; IRAK-1; IRAKPelle homolog; Pelle; Plpk