Human IRAK4 (NP_057207.2) VersaClone cDNA

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Human IRAK4 (NP_057207.2) VersaClone cDNA
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Human IRAK4 (NP_057207.2) VersaClone cDNA Summary


Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: IRAK4

IL-1 receptor-associated kinases (IRAKs) are serine/threonine kinases that help mediate signaling from Toll-like receptor (TLR) and IL-1 receptor family members. Four human IRAKs have been identified: IRAK1, IRAK2, IRAK-M, and IRAK4. All IRAKs are multidomain proteins, containing a conserved N-terminal death domain as well as a central kinase domain that is only active in IRAK1 and IRAK4. IRAK4 mutations have been described in patients with recurrent bacterial infections and poor inflammatory responses.

Long Name
Interleukin-1 Receptor-Associated Kinase 4
Entrez Gene IDs
51135 (Human); 266632 (Mouse); 300177 (Rat)
Alternate Names
EC 2.7.11; EC; interleukin-1 receptor-associated kinase 4; IPD1; IRAK4; IRAK-4; NY-REN-64; REN64; Renal carcinoma antigen NY-REN-64


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