Human KIR3DL3/CD158z Alexa Fluor® 350-conjugated Antibody

Recombinant Monoclonal Antibody
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Product Details
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Human KIR3DL3/CD158z Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity
Detects human KIR3DL3/CD158z in direct ELISAs.
Monoclonal Rabbit IgG Clone # 1136B
Human embryonic kidney cell line HEK293-derived recombinant human KIR3DL3/CD158z
Accession # Q8N743
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Alexa Fluor 350


Recommended Concentration
Flow Cytometry
0.25-1 µg/106 cells
BaF3 mouse pro-B cell line transfected with human KIRDL3/CD158z

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: KIR3DL3/CD158z

KIR3DL3 is a member of the killer-immunoglobulin-like receptors (KIR), a functionally diverse family of transmembrane receptors expressed primarily on NK cells. KIR3DL3 is a “framework” KIR gene, and is present in all individuals, in contrast to non-framework KIRs, whose gene content varies by KIR haplotype. KIR3DL3 is expressed at low or undetectable levels in peripheral blood NK cells, but expression can be induced in NK cell lines by demethylation agents, indicating that promoter DNA methylation inhibits KIR3DL3 transcription. Despite the lack of evidence for surface protein expression, KIR3DL3 mRNA expression has been detected in both decidual and peripheral blood NK cells in normal, disease-free conditions.

Long Name
Killer Cell Immunoglobulin-like Receptor, Three Domain Long Cytoplasmic Tail, 3
Entrez Gene IDs
115653 (Human)
Alternate Names
CD158z; KIR3DL3; KIR3DL7; KIR44; KIRC1

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