Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Flow Cytometry

Cited:

Flow Cytometry

Label

Phycoerythrin (Excitation = 488 nm, Emission = 565-605 nm)

Antibody Source

Monoclonal Rabbit IgG Clone # 1136B
View all KIR3DL3/CD158z Primary Antibodies »

Product Specifications

Immunogen

Human embryonic kidney cell line HEK293-derived recombinant human KIR3DL3/CD158z
Met1-Leu322
Accession # Q8N743

Specificity

Detects human KIR3DL3/CD158z in direct ELISAs.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Human KIR3DL3/CD158z PE‑conjugated Antibody

Detection of KIR3DL3/CD158z antibody in BaF3 Mouse Cell Line Transfected with KIR3DL3/CD158z antibody by Flow Cytometry.

Detection of KIR3DL3/CD158z in BaF3 Mouse Cell Line Transfected with KIR3DL3/CD158z by Flow Cytometry.

BaF3 mouse pro-B cell line transfected with KIR3DL3/CD158z and eGFP was stained with (A) Rabbit Anti-Human KIR3DL3/CD158z PE-conjugated Monoclonal Antibody (Catalog # FAB8919P) or (B) Rabbit IgG PE-conjugated isotype control antibody (Catalog # IC1051P). View our protocol for Staining Membrane-associated Proteins.

Applications for Human KIR3DL3/CD158z PE‑conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: BaF3 Mouse Cell Line Transfected with KIR3DL3/CD158z and eGFP.

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: KIR3DL3/CD158z

KIR3DL3 is a member of the killer-immunoglobulin-like receptors (KIR), a functionally diverse family of transmembrane receptors expressed primarily on NK cells. KIR3DL3 is a “framework” KIR gene, and is present in all individuals, in contrast to non-framework KIRs, whose gene content varies by KIR haplotype. KIR3DL3 is expressed at low or undetectable levels in peripheral blood NK cells, but expression can be induced in NK cell lines by demethylation agents, indicating that promoter DNA methylation inhibits KIR3DL3 transcription. Despite the lack of evidence for surface protein expression, KIR3DL3 mRNA expression has been detected in both decidual and peripheral blood NK cells in normal, disease-free conditions.

Long Name

Killer Cell Immunoglobulin-like Receptor, Three Domain Long Cytoplasmic Tail, 3

Alternate Names

CD158z, KIR3DL7, KIR44, KIRC1

Entrez Gene IDs

115653 (Human)

Gene Symbol

KIR3DL3

UniProt

Q8N743

Additional KIR3DL3/CD158z Products

Product Documents for Human KIR3DL3/CD158z PE‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human KIR3DL3/CD158z PE‑conjugated Antibody

For research use only

Citations for Human KIR3DL3/CD158z PE‑conjugated Antibody

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