Human KIR3DL3/CD158z PE-conjugated Antibody

Catalog # Availability Size / Price Qty
Detection of KIR3DL3/CD158z in BaF3 Mouse Cell Line Transfected with KIR3DL3/CD158z by Flow Cytometry.
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Human KIR3DL3/CD158z PE-conjugated Antibody Summary

Species Reactivity
Detects human KIR3DL3/CD158z in direct ELISAs.
Monoclonal Rabbit IgG Clone # 1136B
Protein A or G purified from cell culture supernatant
Human embryonic kidney cell line HEK293-derived recombinant human KIR3DL3/CD158z
Accession # Q8N743
Supplied in a saline solution containing BSA and Sodium Azide.
Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)


Recommended Concentration
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of KIR3DL3/CD158z antibody in BaF3 Mouse Cell Line Transfected with KIR3DL3/CD158z antibody by Flow Cytometry. View Larger

Detection of KIR3DL3/CD158z in BaF3 Mouse Cell Line Transfected with KIR3DL3/CD158z by Flow Cytometry. BaF3 mouse pro-B cell line transfected with KIR3DL3/CD158z and eGFP was stained with (A) Rabbit Anti-Human KIR3DL3/CD158z PE-conjugated Monoclonal Antibody (Catalog # FAB8919P) or (B) Rabbit IgG PE-conjugated isotype control antibody (Catalog # IC1051P). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: KIR3DL3/CD158z

KIR3DL3 is a member of the killer-immunoglobulin-like receptors (KIR), a functionally diverse family of transmembrane receptors expressed primarily on NK cells. KIR3DL3 is a “framework” KIR gene, and is present in all individuals, in contrast to non-framework KIRs, whose gene content varies by KIR haplotype. KIR3DL3 is expressed at low or undetectable levels in peripheral blood NK cells, but expression can be induced in NK cell lines by demethylation agents, indicating that promoter DNA methylation inhibits KIR3DL3 transcription. Despite the lack of evidence for surface protein expression, KIR3DL3 mRNA expression has been detected in both decidual and peripheral blood NK cells in normal, disease-free conditions.

Long Name
Killer Cell Immunoglobulin-like Receptor, Three Domain Long Cytoplasmic Tail, 3
Entrez Gene IDs
115653 (Human)
Alternate Names
CD158z; CD158Z;Killer cell immunoglobulin-like receptor 3DL3;KIR2DL5B;KIR3DL7;KIR44;KIRC1; KIR3DL3; KIR3DL7; KIR44; KIRC1

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