Human KIR3DL3/CD158z Alexa Fluor® 647-conjugated Antibody

Recombinant Monoclonal Antibody
Catalog # Availability Size / Price Qty
FAB8919R-025
FAB8919R-100
Detection of KIR3DL3/CD158z in BaF3 Mouse Cell Line Transfected with KIR3DL3/CD158z  by Flow Cytometry.
1 Image
Product Details
FAQs
Supplemental Products
Reviews

Human KIR3DL3/CD158z Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human KIR3DL3/CD158z in direct ELISAs.
Source
Recombinant Monoclonal Rabbit IgG Clone # 1136B
Purification
Protein A or G purified from cell culture supernatant
Immunogen
Human embryonic kidney cell line HEK293-derived recombinant human KIR3DL3/CD158z
Met1-Leu322
Accession # Q8N743
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 647

Applications

Recommended Concentration
Sample
Flow Cytometry
5 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Flow Cytometry Detection of KIR3DL3/CD158z in BaF3 Mouse Cell Line Transfected with KIR3DL3/CD158z  by Flow Cytometry. View Larger

Detection of KIR3DL3/CD158z in BaF3 Mouse Cell Line Transfected with KIR3DL3/CD158z by Flow Cytometry. BaF3 mouse pro-B cell line transfected with KIR3DL3/CD158z was stained with Rabbit Anti-Human KIR3DL3/CD158z Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB8919R, filled histogram) or control antibody Rabbit Anti-Human KIR2DS5/CD185g Alexa Fluor® 647‑conjugated Antibody (Catalog # FAB8920R, open histogram). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: KIR3DL3/CD158z

KIR3DL3 is a member of the Killer-Immunoglobulin-like Receptor (KIR) family, a functionally diverse family of transmembrane receptors expressed primarily on NK cells. KIR3DL3 is a “framework” KIR gene, and is present in all individuals, in contrast to non-framework KIRs, whose gene content varies by KIR haplotype. KIR3DL3 is expressed at low or undetectable levels in peripheral blood NK cells, but expression can be induced in NK cell lines by demethylation agents, indicating that promoter DNA methylation inhibits KIR3DL3 transcription. Despite the lack of evidence for surface protein expression, KIR3DL3 mRNA expression has been detected in both decidual and peripheral blood NK cells in normal, disease-free conditions. Over amino acids (aa) 1-322, human KIR3DL3 shares 47% aa sequence identity with mouse KIR3DL1.

Long Name
Killer Cell Immunoglobulin-like Receptor, Three Domain Long Cytoplasmic Tail, 3
Entrez Gene IDs
115653 (Human)
Alternate Names
CD158z; KIR3DL3; KIR3DL7; KIR44; KIRC1

Product Datasheets

FAQs

No product specific FAQs exist for this product, however you may

View all Antibody FAQs

Isotype Controls

Reviews for Human KIR3DL3/CD158z Alexa Fluor® 647-conjugated Antibody

There are currently no reviews for this product. Be the first to review Human KIR3DL3/CD158z Alexa Fluor® 647-conjugated Antibody and earn rewards!

Have you used Human KIR3DL3/CD158z Alexa Fluor® 647-conjugated Antibody?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review