Human LILRA3/CD85e Alexa Fluor® 700-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: LILRA3/CD85e

Human LIR-4 (Leukocyte Ig-like receptor #4; also ILT6 and LILRA3) is an Ig superfamily member that belongs to the leukocyte receptor complex/cluster. Mature LIR-4 is 416 amino acids in length and contains four C2-type Ig-like domains. Unlike other LIR family members, LIR-4 is actively secreted. At least one alternate splice form is known which shows a 64 amino acid deletion in the C-terminal half of the second Ig-like domain. Multiple alleles exist in human, and 5-10% of the population have a defective gene which produces no LIR-4 product. Rodent LIR-4 has not been reported.

Product Datasheets

Related Research Areas

• Angiopoietins, Angiopoietin-like Proteins, and Receptors
• B Cell Activation
• Co-stimulatory and Co-inhibitory Molecules
• Dendritic Cell Activation
• ITIM/ITAM Immunoreceptors and Related Molecules
• Monocyte Markers
• T Cell Antigen Recognition