Human MDM2/HDM2 (AAM78554) VersaClone cDNA Summary
Complete Your Research
MDM2 is a key regulator of p53 tumor suppressor protein activity and stability. MDM2 binds to and inhibits the transactivation domain of p53. In addition, MDM2 controls p53 stability by functioning as its E3 ligase in ubiquitination and by shuttling p53 from the nucleus to the cytoplasm for subsequent degradation. The importance of the p53/MDM2 relationship is underscored by the existence of an autoregulatory feedback loop whereby activated p53 transcriptionally upregulates the expression of its own inhibitor, MDM2.
No product specific FAQs exist for this product, however you mayView all cDNA Clone FAQs
Reviews for Human MDM2/HDM2 (AAM78554) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Human MDM2/HDM2 (AAM78554) VersaClone cDNA and earn rewards!
Have you used Human MDM2/HDM2 (AAM78554) VersaClone cDNA?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image