Cyclin A2 Antibody [Alexa Fluor™ Plus 647]

R&D Systems | Catalog # AF5999AFP647

R&D Systems

Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Alexa Fluor Plus 647 (Excitation = 658 nm, Emission = 675 nm)

Antibody Source

Polyclonal Goat IgG
View all Cyclin A2 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human Cyclin A2

Specificity

Detects human and mouse Cyclin A2 in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Cyclin A2 Antibody [Alexa Fluor™ Plus 647]

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Cyclin A2

Cyclin A2 (also CCNA2) is a member of the cyclin AB subfamily, cyclin family of proteins. Cyclin A2 is ubiquitously expressed, in contrast to CyclinA1 that only appears in late pachytene spermatocytes. It associates with CDK1 during G2 and M phase, and CDK2 in S phase, of the cell cycle. Binding to SCAPER restricts Cyclin A2 to the cytoplasm. In both compartments, it provides substrate specificity to a phosphorylating complex that promotes entry into, and progression through, mitosis. Human Cyclin A2 is 432 amino acids (aa) in length. It contains two cyclin box folds (aa 210‑299 and 309‑430) and four acetylation sites that induce molecule turnover (Lys54/68/95/112). Over aa 73‑199, human Cyclin A2 shares 83% aa identity with mouse Cyclin A2.

Alternate Names

CCNA, CCNA2

Entrez Gene IDs

890 (Human); 12428 (Mouse); 114494 (Rat)

Gene Symbol

CCNA2

UniProt

P20248 (Human)

Additional Cyclin A2 Products

Product Documents for Cyclin A2 Antibody [Alexa Fluor™ Plus 647]

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Cyclin A2 Antibody [Alexa Fluor™ Plus 647]


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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