Human/Mouse/Rat ILK Alexa Fluor® 647-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: ILK

Integrin-linked kinase (ILK) is an ankyrin repeat-containing serine/threonine protein kinase that interacts with the cytoplasmic domain of beta 1 and beta 3 integrins. ILK functions with multiple binding partners to transmit signals from the extracellular matrix to actin filaments, regulating such processes as cellular attachment, cell cycle progression, and cytoskeletal organization. ILK kinase activity is induced by PI3 kinase and negatively regulated by the tumor suppressor PTEN.

Product Datasheets

Related Research Areas

• Actin Stress Fibers and Focal Adhesions During EMT
• Adhesion Molecules in Angiogenesis
• Adhesion Molecules on VSMC
• EMT Induction
• Extracellular Matrix Remodeling and Cell Migration During EMT
• Focal Adhesions
• Integrins and Associated Molecules
• Intracellular Kinases
• Intracellular Kinases in the Akt Pathway
• Kinases and Phosphatases in Endothelial Cells
• Search Kinases and Phosphatases