Human/Mouse SSEA-1 NL557 MAb (Clone MC-480)

R&D Systems | Catalog # NL2155R

R&D Systems
Discontinued Product
NL2155R has been discontinued. View all SSEA-1 products.

Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry

Label

NL557 (Excitation = 557 nm, Emission = 574 nm)

Antibody Source

Monoclonal Mouse IgM Clone # MC-480
View all SSEA-1 Primary Antibodies »

Product Specifications

Specificity

Detects human and mouse SSEA-1.

Clonality

Monoclonal

Host

Mouse

Isotype

IgM

Applications for Human/Mouse SSEA-1 NL557 MAb (Clone MC-480)

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Background: SSEA-1

Stage-Specific Embryonic Antigen-1 (SSEA-1), an antigenic epitope defined as a Lewis x carbohydrate structure, is expressed during early mouse embryogenesis on murine embryonal carcinoma cells (EC), murine embryonic stem cells (ES), and murine and human germ cells. Expression of SSEA-1 is down-regulated following differentiation of murine EC and ES cells. In contrast, the differentiation of human EC and ES cells is accompanied by an increase in SSEA-1 expression (1, 2).

References

  1. Solter, D. and Knowles, B.B. (1978) Proc. Natl. Acad. Sci. USA 75:5565.
  2. Fox, N. et al. (1983) Cancer Res. 43:669.

Long Name

Stage-specific Embryonic Antigen-1

Alternate Names

SSEA1

Additional SSEA-1 Products

Product Documents for Human/Mouse SSEA-1 NL557 MAb (Clone MC-480)

Certificate of Analysis

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Product Specific Notices for Human/Mouse SSEA-1 NL557 MAb (Clone MC-480)

For research use only

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