Human/Mouse ZBTB7A/Pokemon Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB3496V Datasheet / COA / SDS

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FAB3496V-100UG

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Human/Mouse ZBTB7A/Pokemon Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human, Mouse

Specificity

Detects human and mouse ZBTB7A/Pokemon in Western blots.

Source

Monoclonal Mouse IgG2b Clone # 466407

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human ZBTB7A/Pokemon
Met349-Val476
Accession # O95365

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: ZBTB7A/Pokemon

ZBTB7A (zinc finger and BTB domain-containing 7A), also known as Pokemon, FBI-1 in human, LRF in mouse, and OCZF in rat, is a widely expressed nuclear protein that is overexpressed in many human cancers. It is a transcriptional repressor of ARF, c-fos, c-myc, Rb and others, including many extracellular matrix genes. These targets play important roles, both in normal differentiation and oncogenesis. Human ZBTB7A/Pokemon is a 584 amino acid (aa) protein with a BTB-POZ domain (aa 24‑131) and four zinc finger repeats (aa 382‑484). Human ZBTB7A/Pokemon shares 98% aa identity with mouse and rat within aa 349‑476.

Long Name

Zinc Finger and BTB Domain-Containing Protein 7A

Entrez Gene IDs

51341 (Human); 16969 (Mouse); 117107 (Rat)

Alternate Names

DKFZp547O146; Factor binding IST protein 1; Factor that binds to inducer of short transcripts protein 1; FBI-1; FBI-1POK erythroid myeloid ontogenic factor; FBI1TTF-I-interacting peptide 21; HIV-1 inducer of short transcripts binding protein; Leukemia/lymphoma-related factor; LRF; LRFHIV-1 1st-binding protein 1; lymphoma related factor; MGC99631; Pokemon; TIP21; ZBTB7A; ZBTB7zinc finger and BTB domain containing 7; zinc finger and BTB domain containing 7A; zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcriptsbinding protein; zinc finger and BTB domain-containing protein 7A; Zinc finger protein 857A; ZNF857APOZ and Krueppel erythroid myeloid ontogenic factor