Human p38 beta /MAPK11 Alexa Fluor® 405-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: p38 beta/MAPK11

The p38 mitogen-activated protein kinases (p38 MAP kinases) are a family of four related Ser/Thr kinases responsive to pro-inflammatory cytokines and environmental stresses, including ionizing radiation, oxidative stress, and osmotic shock. Each family member, p38 alpha, p38 beta, p38δ, and p38 gamma, is activated by dual Thr and Tyr phosphorylation within a Thr-Gly-Tyr motif residing in the kinase activation loop. For p38 beta, also known as p38-2, stress-activated protein kinase 2B (SAPK2B), and MAPK11, this dual phosphorylation occurs at Thr180/Tyr182.

Product Datasheets

Related Research Areas

• Airway Inflammation and Remodeling
• Apoptosis Intracellular Kinases
• Chemokine Receptor Intracellular Signaling
• C-type Lectin Receptors
• Diabetic Peripheral Neuropathy
• GDNF Family
• IL-1 Family
• IL-10 Family
• IL-17 Family
• Interferons
• Intracellular Kinases
• Intracellular Kinases in the Akt Pathway
• Neurotrophin/Trk Family
• NOD-like Receptors and the Inflammasome
• Platelet Signaling
• Positive Regulators of the Jak/STAT Pathway
• Search Kinases and Phosphatases
• TNF Superfamily Regulators
• Toll-Like Receptors
• VEGF Family