Human PGD2 Synthase/PTGDS (NP_000945) VersaClone cDNA

R&D Systems | Catalog # RDC2628

R&D Systems
100% Guarantee

Key Product Details

Species

Human

Accession Number

NP_000945

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: PGD2 Synthase/PTGDS

Prostaglandin D Synthase (PTGDS), is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS has also been implicated in the development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement (NREM) sleep. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a Beta-Amyloid chaperone and may have a role in the deposition of amyloid-b plaques in Alzheimer's disease.

Long Name

Prostaglandin D2 Synthase

Alternate Names

Cerebrin-28, PDS, PGD2, PGDS2, PH2DISO, PTGDS

Entrez Gene IDs

5730 (Human); 25526 (Rat)

Gene Symbol

PTGDS

UniProt

NP_000945

Additional PGD2 Synthase/PTGDS Products

Product Documents for Human PGD2 Synthase/PTGDS (NP_000945) VersaClone cDNA

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human PGD2 Synthase/PTGDS (NP_000945) VersaClone cDNA

For research use only

Customer Reviews for Human PGD2 Synthase/PTGDS (NP_000945) VersaClone cDNA

There are currently no reviews for this product. Be the first to review Human PGD2 Synthase/PTGDS (NP_000945) VersaClone cDNA and earn rewards!

Have you used Human PGD2 Synthase/PTGDS (NP_000945) VersaClone cDNA?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

FAQs

No product specific FAQs exist for this product.

View all FAQs for cDNA Clones