Human CNAP1/CEP250 Antibody (2739C) [Alexa Fluor™ Plus 405]

R&D Systems | Catalog # FAB11339AFP405

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 405 (Excitation = 404 nm, Emission = 455 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2739C
View all CNAP1/CEP250 Primary Antibodies »

Product Specifications

Immunogen

Phosphopeptide containing the human CEP250/CNAP1 S2421 site

Specificity

Detects Human Phospho-CEP250/CNAP1 in direct ELISA 

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for Human CNAP1/CEP250 Antibody (2739C) [Alexa Fluor™ Plus 405]

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CNAP1/CEP250

CEP250 (also known as CNAP1) is a large centrosome-associated protein that plays a crucial role in centrosome duplication and organization during cell division. Centrosomes are organelles play an essential role in cell division, cell polarity, and intracellular transport. In most animal cells, centrosomes consist of a pair of centrioles surrounded by pericentriolar material (PCM).CEP250/CNAP1 is a critical component of the PCM and is required for centrosome duplication and maturation. It forms a bridge between the centrioles and PCM and recruits other PCM components to the centrosome. Phosphorylation of CEP250/CNAP1 may regulate association/dissociation from centrosome. During M phase of mitosis, it is phosphorylated by NEK2, which may trigger the dissociation from the mitotic centrosome. This antibody detects CEP250/CNAP1 phosphorylated at Ser2421.  

Long Name

Centrosomal Nek2-Associated Protein 1

Alternate Names

C-NAP1, CEP2, CEP250

Entrez Gene IDs

11190 (Human)

Gene Symbol

CEP250

UniProt

Q9BV73

Additional CNAP1/CEP250 Products

Product Documents for Human CNAP1/CEP250 Antibody (2739C) [Alexa Fluor™ Plus 405]

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human CNAP1/CEP250 Antibody (2739C) [Alexa Fluor™ Plus 405]


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Related Research Areas

Cell Cycle

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