Human Phospho-STAT4 (Y693) Alexa Fluor® 750-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: STAT4

Signal transduction and activator of transcription 4 (STAT4) is a member of the Jak/STAT signal transduction pathway. STAT4 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, homo or heterodimerizes with other STAT proteins, which then translocate to the nucleus and activate transcription of specific genes. STAT4 is expressed in subset of tissues including spleen, heart, brain, peripheral blood cells and testis. STAT4 is involved in mediating IL-12 response in lymphocytes and regulating T helper cell differentiation.

Product Datasheets

Related Research Areas

• Apoptosis Transcription Factors and Regulators
• Hematopoietic Stem Cell Transcription Factors and Regulators
• IL-12 Family
• Immunoglobulin-Like Domain Transcription Factors
• Interferons
• Jak and STAT Proteins
• STAT
• Th1 Cells