Home / PIEZO2 / Human PIEZO2 Alexa Fluor® 405-conjugated Antibody

Human PIEZO2 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB11559V Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB11559V-100UG
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human PIEZO2 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects a synthetic peptide specific for Piezo2 around amino acid 2115 in Direct ELISA.
Source
Monoclonal Mouse IgG2b Clone # 1081503
Purification
Protein A or G purified
Immunogen
PIEZO2 containing synthetic peptide
Accession # Q9H5I5
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PIEZO2

PIEZO2 is an 318 kDa mechanosensitive nonselective cation channel, found in cell types that typically respond to physical touch. PIEZO2 is an essential mechanotransducer for touch, proprioception, and interoception.  PIEZO2 is important for aspects of breathing, bladder control, blood pressure regulation and many other processes since it is expressed in several classes of jugular and nodose ganglia neurons. Loss of function of PIEZO2 results in profound lack of proprioception and is diagnosed as a rare disease caused PIEZO2 deficiency syndrome.

Long Name
PIEZO2
Entrez Gene IDs
63895 (Human); 667742 (Mouse); 307380 (Rat)
Alternate Names
C18orf30; C18orf58; DA3; DA5; DAIPT; FAM38B; FAM38B2; family with sequence similarity 38, member A pseud; family with sequence similarity 38, member B; family with sequence similarity 38, member B2; FLJ23144; FLJ23403; FLJ25916; FLJ34907; FLJ37734; FLJ45725; HsT748; HsT771; MWKS; PIEZO2; piezo-type mechanosensitive ion channel component ; piezo-type mechanosensitive ion channel component 2; protein PIEZO2

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