Home / RBFOX3/NeuN / Human RBFOX3/NeuN MAb (Clone 1094645)

Human RBFOX3/NeuN MAb (Clone 1094645)

Catalog #: FAB11665V Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB11665V-100UG
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human RBFOX3/NeuN MAb (Clone 1094645) Summary

Species Reactivity
Human
Specificity
Detects a synthetic peptide specific for human RBFOX3 around amino acid 5 in Direct ELISA. 
Source
Monoclonal Mouse IgG1 Clone # 1094645
Purification
Protein A or G purified
Immunogen
Synthetic Peptide
Accession # A6NFN3
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: RBFOX3/NeuN

RBFOX3, also known as Neuronal nuclei (NeuN), is a 34kDa marker of post-mitotic neurons that is highly conserved  among different species.  The RBFOX family regulates alternative slicing and is encoded by three genes: RBFOX1, RBFOX2 and RBFOX3.  RBFOX3 mediates hippocampal circuitry, neurogenesis, and synaptogenesis. RBFOX3 plays a crucial role in normal synaptic function and is implicated in human neurological functions and mutations have been linked to neurodevelopmental delay, cognitive impairment, autistic features, and epilepsy.

Long Name
RNA binding fox-1 homolog 3
Entrez Gene IDs
146713 (Human); 52897 (Mouse); 287847 (Rat)
Alternate Names
FLJ56884; FLJ58356; Fox-1 homolog C; FOX3; FOX-3; hexaribonucleotide binding protein 3; HRNBP3; neuN antigen; NEUN; neuronal nuclei antigen; neuronal nuclei; RBFOX3; RNA binding protein fox-1 homolog 3; RNA binding protein, fox-1 homolog (C. elegans) 3; RNA binding protein, fox-1 homolog 3

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