Human Relaxin R2 Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB10250N Datasheet / COA / SDS

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FAB10250N-100UG

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All Relaxin R2 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Relaxin R2 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human RelaxinR2 in direct ELISAs.

Source

Monoclonal Mouse IgG2b Clone # 1013901

Purification

Protein A or G purified

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Relaxin R2
Met1-Asn416
Accession # Q8WXD0

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Relaxin R2

Relaxin R2 (also known as LGR8) is the G-protein coupled receptor (GPCR) for Relaxin, and may also be a receptor for INSL3. LGR8 can mediate the action of Relaxin through cAMP-dependent pathway distinct from structurally related insulin and insulin-like growth factor family ligand. Distribution of this receptor implicates its role in reproductive, brain, renal, cardiovascular and other functions.

Long Name

Relaxin Receptor 2

Entrez Gene IDs

122042 (Human); 140498 (Mouse)

Alternate Names

G protein coupled receptor affecting testicular descent; Gpr106; GPR106G-protein coupled receptor 106; Great; GREATRelaxin family peptide receptor 2; INSL3R; leucine-rich repeat-containing G protein-coupled receptor 8; Leucine-rich repeat-containing G-protein coupled receptor 8; Lgr8; LGR8.1; LGR8G-protein coupled receptor affecting testicular descent; Relaxin R2; relaxin receptor 2; relaxin/insulin-like family peptide receptor 2; RelaxinR2; RLN2R; Rxfp2; RXFPR2