Human Relaxin R2 Antibody

Catalog # Availability Size / Price Qty
Relaxin R2 in Human Heart.
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Product Details
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Human Relaxin R2 Antibody Summary

Species Reactivity
Detects human RelaxinR2 in direct ELISAs.
Monoclonal Mouse IgG2B Clone # 1013901
Protein A or G purified from hybridoma culture supernatant
Chinese hamster ovary cell line CHO-derived recombinant human Relaxin R2
Accession # Q8WXD0
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
5-25 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry Relaxin R2 antibody in Human Heart by Immunohistochemistry (IHC-P). View Larger

Relaxin R2 in Human Heart. Relaxin R2 was detected in immersion fixed paraffin-embedded sections of human heart using Mouse Anti-Human Relaxin R2 Monoclonal Antibody (Catalog # MAB10250) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in cardiomyocytes. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Relaxin R2

Relaxin R2 (also known as LGR8) is the G-protein coupled receptor (GPCR) for Relaxin, and may also be a receptor for INSL3. LGR8 can mediate the action of Relaxin through cAMP-dependent pathway distinct from structurally related insulin and insulin-like growth factor family ligand. Distribution of this receptor implicates its role in reproductive, brain, renal, cardiovascular and other functions.

Long Name
Relaxin Receptor 2
Entrez Gene IDs
122042 (Human); 140498 (Mouse)
Alternate Names
G protein coupled receptor affecting testicular descent; Gpr106; GPR106G-protein coupled receptor 106; Great; GREATRelaxin family peptide receptor 2; INSL3R; leucine-rich repeat-containing G protein-coupled receptor 8; Leucine-rich repeat-containing G-protein coupled receptor 8; Lgr8; LGR8.1; LGR8G-protein coupled receptor affecting testicular descent; Relaxin R2; relaxin receptor 2; relaxin/insulin-like family peptide receptor 2; RelaxinR2; RLN2R; Rxfp2; RXFPR2

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