The GDNF family members (GDNF, neurturin, artemin, and persephin) signal through multicomponent receptors that consist of the Ret receptor tyrosine kinase and one of four glycosyl-phosphatidylinositol (GPI)-linked ligand-binding subunits (GFR alpha-1-4). GFR alpha-1, -2, -3 and -4 are the preferred ligand-binding subunits for GDNF, neurturin, artemin, and persephin, respectively. The Ret tyrosine-kinase receptor is encoded by the c-ret proto-oncogene. Human and mouse Ret share 83% amino acid sequence homology.
Human Ret (NP_066124) VersaClone cDNA
R&D Systems | Catalog # RDC0394
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Background: Ret
Long Name
Proto-oncogene Tyrosine-protein Kinase Receptor Ret
Alternate Names
CDHF12MTC1, CDHR16, EC 2.7.10, Hirschsprung disease 1, Hirschsprung disease), MEN2A, MEN2B, multiple endocrine neoplasia and medullary thyroid carcinoma 1, ret proto-oncogene, RET transforming sequence
Gene Symbol
RET
UniProt
Additional Ret Products
Product Documents for Human Ret (NP_066124) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human Ret (NP_066124) VersaClone cDNA
For research use only
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