Human Serpin C1/Antithrombin-III Quantikine ELISA Kit
Human Serpin C1/Antithrombin-III Quantikine ELISA Kit Summary
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Product Summary
Precision
Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine, Human Milk
| Intra-Assay Precision | Inter-Assay Precision | |||||
|---|---|---|---|---|---|---|
| Sample | 1 | 2 | 3 | 1 | 2 | 3 |
| n | 20 | 20 | 20 | 20 | 20 | 20 |
| Mean (ng/mL) | 1.95 | 6.37 | 12.2 | 1.84 | 5.82 | 11.8 |
| Standard Deviation | 0.077 | 0.224 | 0.303 | 0.079 | 0.432 | 0.778 |
| CV% | 3.9 | 3.5 | 2.5 | 4.3 | 7.4 | 6.6 |
Recovery
The recovery of human Serpin C1 spiked to levels throughout the range of the assay in various matrices was evaluated.
| Sample Type | Average % Recovery | Range % |
|---|---|---|
| Cell Culture Media (n=4) | 93 | 83-108 |
| Urine (n=4) | 99 | 92-109 |
Linearity
Scientific Data
Product Datasheets
Preparation and Storage
Background: Serpin C1/Antithrombin-III
The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins.
Citation for Human Serpin C1/Antithrombin-III Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
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Plasma Protein Biomarkers Associated with Higher Ovarian Cancer Risk in BRCA1/2 Carriers
Authors: HS Ahn, JY Ho, J Yu, J Yeom, S Lee, SY Hur, Y Jung, K Kim, YJ Choi
Cancers, 2021;13(10):.
Species: Human
Sample Types: Plasma
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