Human Siglec-3/CD33 (Research Grade Gemtuzumab Biosimilar) Antibody
Human Siglec-3/CD33 (Research Grade Gemtuzumab Biosimilar) Antibody Summary
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of Siglec-3/CD33 on U937 Human Cell Line by Flow Cytometry. U937 Human histiocytic lymphoma cell line was stained with Human Anti-Human Siglec-3/CD33 (Research Grade Gemtuzumab Biosimilar) Monoclonal Antibody (Catalog # MAB9635, filled histogram) or irrelevant antibody (open histogram) followed by APC-conjugated Anti-Human IgG Secondary Antibody (Catalog # F0135). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Gemtuzumab is a biosimilar directed against the extracellular domain of CD33. This product constitutes the immunogen used for the anti-Idiotype catalog numbers MAB9617 and MAB96171. The biotinylated antibody (catalog number FAB9635B) can be used in flow cytometry or various assay format to measure Siglec‑3/CD33 expression and can be detected by conjugated streptavidin.
Does this Biosimilar antibody have the same sequence as the therapeutic antibody?
The Biosimilar antibody has the same variable region and constant region sequence as the therapeutic antibody.
What is a Biosimilar antibody?
A Biosimilar antibody is a non-therpeutic, recombinantly-expressed antibody which has the same sequence as the corresponding therapeutic antibody. It is for research use only. The nomenclature of the Biosimilar antibody includes the name of the therapeutic antibody. For example, Catalog # MAB9577 is called Human EGFR (Research Grade CetuxiMab Biosimilar) antibody.
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