Human SOX13 Alexa Fluor® 700-conjugated Antibody

Recombinant Monoclonal Antibody
Catalog # Availability Size / Price Qty
FAB5118N-100UG

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Human SOX13 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human SOX13 in direct ELISAs.
Source
Monoclonal Rabbit IgG Clone # 2559A
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human SOX13
Met19-Pro258
Accession # Q9UN79
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: SOX13

SOX-13 is a transcription factor involved in the embryonic development and the determination of cell fate.  It is also known as islet cell antibody 12 since it has been determined to be a type-1 diabetes autoantigen.  SOX-13 RNA is detected in most human tissues with highest levels in the pancreas, placenta, and kidney.  Immunohistochemistry on human pancreas identifies SOX-13 in the islets of Langerhans where staining is mostly cytoplasmic but can also be nuclear. SOX-13 antibody testing helps identify latent autoimmune diabetes of adults (LADA).

Long Name
SRY (sex determining region Y)-box 13
Entrez Gene IDs
9580 (Human); 20668 (Mouse); 289026 (Rat)
Alternate Names
ICA12; Islet cell antigen 12; MGC117216; SOX13; Sox-13; SRY (sex determining region Y)-box 13ICA12islet cell 12; SRY-box 13; SRY-related HMG-box gene 13; transcription factor SOX-13; Type 1 diabetes autoantigen ICA12

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