Human SOX17 NL493 Affinity Purified Polyclonal Ab

R&D Systems | Catalog # NL1924G

R&D Systems
Discontinued Product
NL1924G has been discontinued. View all SOX17 products.

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry

Label

NL493 (Excitation = 493 nm, Emission = 514 nm)

Antibody Source

Polyclonal Goat IgG
View all SOX17 Primary Antibodies »

Product Specifications

Specificity

Detects human SOX17 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) SOX2, rhSOX6, and rhSOX15 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human SOX17 NL493 Affinity Purified Polyclonal Ab

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: SOX17

SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development (1, 2). In Western blot, AF1924 detects a 60 kDa band of endogenous SOX17 which is higher than predicted molecular weight but consistent with the current literature (3).

 

References

  1. Kanai-Azuma, M. et al. (2002) Development 129:2367.
  2. Katoh, M. et al. (2002) Int. J. Mol. Med. 9:153.
  3. Sohn, J. et al. (2006) J. Neuroscience 26:9722.

Long Name

Transcription Factor SOX17

Alternate Names

FLJ22252, SRY (sex determining region Y)-box 17, SRY-related HMG-box transcription factor SOX17, transcription factor SOX-17, VUR3

Entrez Gene IDs

64321 (Human)

Gene Symbol

SOX17

UniProt

Q9H6I2

Additional SOX17 Products

Product Documents for Human SOX17 NL493 Affinity Purified Polyclonal Ab

Certificate of Analysis

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Product Specific Notices for Human SOX17 NL493 Affinity Purified Polyclonal Ab

For research use only

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